AD, Project Team Leader Early-Stage Product Development

3 weeks ago

Emeryville, United States 4D Molecular Therapeutics Full time

Attention recruitment agencies: All agency inquiries are vetted through 4DMT’s internal Talent Acquisition team. No unsolicited resumes will be accepted. The 4DMT Talent Acquisition team must expressly engage agencies on any requisition. Agencies contacting hiring managers directly will not be tolerated, and doing so may impact your ability to work with 4DMT in the future.

 

4DMT is a clinical-stage biotherapeutics company harnessing the power of directed evolution for targeted genetic medicines. We seek to unlock the full potential of gene therapy using our platform, Therapeutic Vector Evolution (TVE), which combines the power of directed evolution with our approximately one billion synthetic AAV capsid-derived sequences to invent evolved vectors for use in our products. We believe key features of our targeted and evolved vectors will help us create targeted product candidates with improved therapeutic profiles. These profiles will allow us to treat a broad range of large market diseases, unlike most current genetic medicines that generally focus on rare or small market diseases.  

Company Differentiators: 

•    Fully integrated clinical-phase company with internal manufacturing
•    Demonstrated ability to move rapidly from idea to IND
•    Five candidate products in the clinic and two declared pre-clinical programs
•    Robust technology and IP foundation, including our TVE and manufacturing platforms
•    Initial product safety and efficacy data substantiates the value of our platforms
•    Opportunities to expand to other indications and modalities within genetic medicine

GENERAL SUMMARY: 

Reporting to the VP, Early-Stage Product Development, the Associate Director will play an important role in early-stage drug product development programs from preclinical studies to clinical proof-of-concept.  

RESPONSIBILITIES:   

Contribute to the execution of early-stage drug product development programs through preclinical studies to clinical proof-of-concept  Contribute to the assessment and prioritization of the 4DMT product pipeline.   Work closely with the VP of Early-Stage Product Development, Therapeutic Area Heads and the Chief Research & Translational Development Officer to translate drug candidates into early phase clinical trials.   Oversee the design and implementation of preclinical in vivo and in vitro studies, including IND-enabling studies.    Lead cross-functional teams and work closely with the program management team to execute all product pipeline activities including IND-enabling studies.  Contribute to the preparation of content for regulatory interactions and submissions (e.g. pre-IND and/or INTERACT meetings, IND filing, Orphan Drug Designation requests, EMA submission) as necessary.   Continue to support late-stage product development serving as nonclinical subject matter experts and contributing to late-stage regulatory filings  Present to and interact with senior management and Executive Team members to assess progress toward meeting strategic objectives and company goals, identify program risks, and develop risk mitigation plans.   Present data and program updates internally and externally to scientific and non-scientific audiences.   Other duties as assigned.  

  

Education and Experience Requirements: 

PhD in biological sciences required.   5+ years industry experience required  3+ years in project leadership or management role (lab science experience will also be considered)    Experience working on a cross-functional team and developing strong cross-functional relationships   Experience partnering with program management team to execute all product pipeline activities including IND-enabling studies   Experience in preparation of content for regulatory interactions and submissions (e.g. pre-IND and/or INTERACT meetings, IND filing, Orphan Drug Designations requests, EMA submission)  

Required Skills/Abilities: 

Strong scientific acumen and strategic thinking skills   Proactive and flexible with changing work priorities   Able to navigate ambiguity and able to take the initiative to define structure   Excellent analytical, logical thinking, and problem-solving skills    Excellent communication skills in both writing and presentations    Ability to motivate groups of people to complete a project in a timely manner.   Ability to work in a small company and fast-paced environment.  

 

Base salary compensation range:

$178,000/yr - $220,000/yr 

Please note that compensation varies depending on experience and other factors. 4DMT provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, genetic information, marital status, status as a covered veteran, and any other category protected under applicable federal, state, provincial and local laws.   Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities

  • Associate Director, Early-Stage Product Development

    2 months ago

    Emeryville, California, United States 4D Molecular Therapeutics Full time

    Attention recruitment agencies: All agency inquiries are vetted through 4DMT's internal Talent Acquisition team. No unsolicited resumes will be accepted. Agencies must be expressly engaged by the 4DMT Talent Acquisition team on any requisition. Agencies reaching out directly to hiring managers will not be tolerated and doing so may impact your ability to...

  • Senior Manager of Cell Therapy Development

    5 days ago

    Emeryville, California, United States BeiGene Full time

    About the RoleWe are seeking an exceptional and highly motivated leader to join our Cell Therapy team at BeiGene. As the Director of Cell Therapy Operations, you will play a critical role in enabling the development of our cell therapy programs.Key ResponsibilitiesStrengthen our internal cell therapy capability by working with internal stakeholders and...

  • Construction Project Manager

    4 days ago

    Emeryville, California, United States IPS-Integrated Project Services Full time

    About the RoleWe are seeking a highly skilled Construction Superintendent to join our team at IPS-Integrated Project Services. As a key member of our construction management team, you will be responsible for overseeing the execution of construction projects, ensuring they are completed on time, within budget, and to the highest quality standards.Key...

  • Production Engineering Supervisor

    7 days ago

    Emeryville, California, United States unspun Full time

    Position OverviewWe are seeking a seasoned and dedicated Production Engineering Supervisor to lead our initiatives. In this capacity, your main focus will be on managing projects aimed at enhancing and expanding our innovative textile production technique, VegaTM, through meticulous project planning, requirement oversight, and strategic resource...

  • Product Development Specialist

    1 week ago

    Emeryville, California, United States Kelly Science, Engineering, Technology & Telecom Full time

    Job SummaryWe are seeking a highly skilled Research and Development Scientist to join our team at Kelly Science, Engineering, Technology & Telecom. As a key member of our product development team, you will be responsible for driving innovation and delivering high-quality products to the market.Key ResponsibilitiesDevelop and execute product development...

  • Mechanical Engineering Team Lead

    2 weeks ago

    Emeryville, California, United States UPSIDE Foods Full time

    About UsUPSIDE Foods, located in Berkeley, CA, is pioneering the production of meat, poultry, and seafood derived directly from real animal cells. Our mission is to create delicious meat products without the necessity of raising and slaughtering vast numbers of animals. By doing so, we aim to tackle significant environmental, animal welfare, and public...

  • Retail Team Leader Trainee

    2 weeks ago

    Emeryville, California, United States UNIQLO Full time

    Salary: $22.50 / hour UNIQLO Bay Street *The offered salary or salary range is based on several factors, including, but not limited to, overall experience, relevant experience, education level, certifications, applicable skills and expertise, and location of the position. As an Equal Opportunity Employer, UNIQLO USA, does not discriminate against...

  • Head of Analytical Development and Quality Control

    3 hours ago

    Emeryville, California, United States Tbwa ChiatDay Inc Full time

    Job SummaryWe are seeking an experienced and visionary leader to head our Analytical Sciences and Quality Control (ASQC) function. As the Head of Analytical Development and Quality Control, you will be responsible for developing and implementing phase-appropriate analytical methods and testing strategies for complex biologicals, including plasmid DNA, mRNA,...

  • Retail Sales Team Leader

    2 months ago

    Emeryville, United States IKEA Full time

    IKEA - JobID: 246404 [Department Manager] As a Team Leader at IKEA, you'll: Manage, direct and coordinate the day-to-day merchandising operations; Implement actions based on customer input and feedback; Plan and implement product changes; Ensure that all coworkers experience new products so they can communicate benefits, ingredients and allergens to...

  • Senior Process Engineer

    10 hours ago

    Emeryville, California, United States IPS-Integrated Project Services, LLC Full time

    About the RoleWe are seeking a highly skilled Senior Process Engineer to join our team at IPS-Integrated Project Services, LLC. As a key member of our design team, you will be responsible for designing and implementing manufacturing processes and supporting utilities for our pharmaceutical and biotechnology clients.Key ResponsibilitiesAssist the Lead Process...

  • Sr. Director, Program Management

    2 months ago

    Emeryville, United States 4D Molecular Therapeutics Full time

    Attention recruitment agencies: All agency inquiries are vetted through 4DMT’s internal Talent Acquisition team. No unsolicited resumes will be accepted. Agencies must be expressly engaged by the 4DMT Talent Acquisition team on any requisition. Agencies reaching out directly to hiring managers will not be tolerated and doing so may impact your ability to...

  • Senior Process Engineer

    5 days ago

    Emeryville, United States IPS-Integrated Project Services, LLC Full time

    Job Description At IPS, you will apply your knowledge, skills, and passion to make a difference in the lives of people by solving complex challenges related to pharmaceutical, biotech, and animal health research and manufacturing facilities. We are looking for a dedicated Senior Process Engineer to join our talented team at our office located in Emeryville,...

  • Project Architect

    1 week ago

    Emeryville, California, United States Ratcliff Architects Inc. Full time

    Project ArchitectRatcliff Architects Inc. is a renowned leader in the planning and design of complex healthcare facilities, including acute and ambulatory care facilities and medical campus master plans.Job SummaryWe are seeking a highly skilled and experienced Project Architect to contribute to the success of our healthcare-focused projects.Key...

  • Early Childhood Educator

    3 days ago

    Emeryville, California, United States KinderCare Education Full time

    About KinderCare EducationKinderCare Education is a leading provider of early childhood education and childcare services. Our mission is to provide high-quality, research-backed programs that support the development of young children and their families.Job SummaryWe are seeking a dedicated and passionate Early Childhood Educator to join our team as a Teacher...

  • Senior Process Engineer

    4 days ago

    Emeryville, United States IPS - Integrated Project Services, LLC Full time

    Job DescriptionAt IPS, you will apply your knowledge, skills, and passion to make a difference in the lives of people by solving complex challenges related to pharmaceutical, biotech, and animal health research and manufacturing facilities. We are looking for a dedicated Senior Process Engineer to join our talented team at our office located in Emeryville,...

  • Supply Chain Manager, Vega

    2 weeks ago

    Emeryville, California, United States unspun Full time

    We are seeking a skilled and dedicated Supply Chain Manager to oversee our operations. In this position, your main duty will be to create and execute plans for effective sourcing, management, and production of intricate hardware subassemblies for our industrial 3D weaving machine. We are looking for an individual with a robust background in supply chain...

  • Supply Chain Manager, Vega

    7 days ago

    Emeryville, California, United States unspun Full time

    We are seeking a skilled and dedicated Supply Chain Manager to oversee our operations. In this position, your main duty will be to devise and execute strategies for effective sourcing, managing, and producing intricate hardware subassemblies for our industrial 3D weaving technology. We require a candidate with a robust background in supply chain management...

  • Senior Process Engineer

    2 months ago

    Emeryville, United States IPS-Integrated Project Services, LLC Full time

    Job Description: At IPS, you will apply your knowledge, skills, and passion to make a difference in the lives of people by solving complex challenges related to pharmaceutical, biotech, and animal health research and manufacturing facilities. We are looking for a dedicated Senior Process Engineer to join our talented team at our office located in ....

  • Research And Development Scientist

    1 week ago

    Emeryville, United States Kelly Science, Engineering, Technology & Telecom Full time

    Scientist R&IKelly® Science & Clinical is seeking a R&I Scientist for a contract position at a premier client in Emeryville, CA. If you’re passionate about bringing the latest scientific discoveries to life and are ready to take the next step in your career, trust The Experts at Hiring Experts.Pay Rate: Depends on Experience OverviewThis client is an...

  • Research And Development Scientist

    1 week ago

    Emeryville, United States Kelly Science, Engineering, Technology & Telecom Full time

    Scientist R&IKelly® Science & Clinical is seeking a R&I Scientist for a contract position at a premier client in Emeryville, CA. If you’re passionate about bringing the latest scientific discoveries to life and are ready to take the next step in your career, trust The Experts at Hiring Experts.Pay Rate: Depends on Experience OverviewThis client is an...