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Pharmacokinetics Scientist
3 months ago
- **Only those lawfully authorized to work in the designated country associated with the position will be considered.**
- **Please note that all Position start dates and duration are estimates and may be reduced or lengthened based upon a client’s business needs and requirements.**
Education
A Bachelor’s or Master’s degree in Biology or BiochemistryJob Responsibilities/Required Skills:
3+ years in the Research and Development experience.Design and implement in-vitro and in-vivo studies to address ADME questions of protein and nucleotide therapeutic. Writing and submitting protocol to cross functional team for review.Carry out sample analysis (including tissue processing) by using different analytical methods.Characterize and identify possible biotransformation products from protein and nucleotide therapeutic in different biological matrices.Must have demonstrated a general working knowledge of cell-based assay, analytical techniques (HPLC, LSC, mass spectrometry and etc.), and laboratory skills. Interpret data and communicate results in department meeting and project team meeting.Prepare presentation and report for conferences, manuscripts and regulatory documents.The candidate should be proficient in a broad variety of lab related technical skills (cell culturing, cell base assay, analytical chemistry, etc.). You are expected to have some knowledge in basic pharmacology, drug metabolism (characterizing and identifying metabolite) and in PKPD relationship. An individual with strong communication and collaboration skill, along with the ability to clearly articulate solution.Good oral and written communication skills are important as well as demonstrated effectiveness in working independently and in a team setting.Preferred Skills:
Understanding of PK concepts and the use of novel drug delivery system is preferred.Previous experience in chemistry, especially with working with radio-isotope, is a plus.Description:
We are looking for an exceptional laboratory-based contract scientist to work in the investigative PK/ADME group. This position is to investigate the pharmacokinetics, biodistribution, metabolism, and the PKPD relationships of novel therapeutics in preclinical setting in support of early and late stage drug development. The candidate will be responsible for designing and implementing in-vitro and in-vivo studies that includes cell based in-vitro assay, radiolabeled tissue distribution studies, ADME studies to understand the properties of protein and nucleotide therapeutics. The candidate will interact and develop close partnerships across various functions including Research, Safety Assessment, PD Biomarker, Bioanalytical Assays, Clinical Sciences, Formulation and Regulatory. Additional component of the job will be sample/data analysis and presentation of results to cross-functional teams, department meetings, review committees, internal/external conferences, and regulatory agencies.Benefits:
For information and details on employment benefits offered with this position, please visit here. Should you have any questions/concerns, please contact our HR Department via our secure website.
California Pay Equity:
For information and details on pay equity laws in California, please visit the State of California Department of Industrial Relations' website here.
Rose International is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender (expression or identity), national origin, arrest and conviction records, disability, veteran status or any other characteristic protected by law. Positions located in San Francisco and Los Angeles, California will be administered in accordance with their respective Fair Chance Ordinances.
If you need assistance in completing this application, or during any phase of the application, interview, hiring, or employment process, whether due to a disability or otherwise, please contact our HR Department.
Rose International has an official agreement (ID #132522), effective June 30, 2008, with the U.S. Department of Homeland Security, U.S. Citizenship and Immigration Services, Employment Verification Program (E-Verify). (Posting required by OCGA 13/10-91.).
