Scientist/Senior Scientist
2 weeks ago
Scientist/Senior Scientist - In Vivo Biology (Neuroscience)
Company Overview
GC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in Professor George Church’s lab, a pioneer in synthetic biology, and allows for the development of unique cell therapies with significantly streamlined manufacturing, improved cell quality, efficiency and speed. GC Therapeutics is based in Cambridge, MA. For additional information, please visit www.gc-tx.com.
Job Purpose
GC Therapeutics is seeking a talented and highly motivated scientist for our neuroscience program. This role will involve bringing a new class of cellular therapies to patients using GCTx’s Human TFome™ platform, a synthetic biology-driven technology to differentiate human stem cells. The candidate will have strong expertise in in vivo studies using preclinical animal models of disease. Initially, this candidate will design experiments to assess GCTx’s cell therapies in small animal models and supervise the execution of these experiments by CROs and collaborators. The role will involve setting up an in-house vivarium. The candidate will be responsible for animal handling and personally designing and executing animal studies.
Duties and Responsibilities
General Laboratory Roles:
- Responsible for experimental design, data generation, analysis, and communication of results to supervisor, and team members.
- Maintain a detailed laboratory journal, summarize results and create presentations for internal group meetings.
- Exemplify scientific curiosity and deep expertise with relevant literature and cutting-edge technologies to advance research directions.
- Work with other members of the research team and within GCTx to accomplish company goals.
- Follow all safe laboratory practices and company policies.
Essential Qualifications:
- Ph.D. degree in neuroscience, cell biology, or related discipline and 5+ years of laboratory work experience in academia or industry.
- Expertise in creating packages for preclinical in vivo studies for IND applications.
- Oversee GLP and non-GLP in vivo (e.g. rodent and non-human primate) studies internally or out-sourced from lead selection screening through lead candidate IND-enabling work.
- Maintain and manage relationships with preclinical CROs, serving as the primary liaison between the company and external vendors.
- Support regulatory writing of nonclinical sections of regulatory submissions.
- Stereotaxic surgery expertise in animals (e.g. rodents) for mono- or multifocal injections.
- CNS tissue processing and immunohistochemistry.
- Strong work ethic with the ability to perform tasks independently and manage both junior staff and external collaborators.
- Proficient in analysis, presentation and documentation of scientific data as well as preparation of scientific reports.
- Strong project and time management skills.
- Ability to work in a laboratory environment approximately 75% of the time, including some weekend hours.
Additional Preferred Qualifications:
- Proven track record and strong publications in neuroscience, animal work and preclinical studies in Industry.
- Expertise in cell therapy, and routes of administration for preclinical animal models of disease.
Equal Opportunity Workplace: GC Therapeutics is an equal opportunity employer. We provide equal employment opportunities to all applicants for employment and existing employees without regard to ancestry, national origin, place of birth, race, color, gender, sexual orientation, marital status, pregnancy, religion, age, disability, gender identity, results of genetic testing, service in the military or otherwise to the full extent of all federal, state and local laws. GC Therapeutics’ equal employment opportunity policy applies to all terms and conditions of recruiting, hiring, placement, training, compensation, transfer, leave of absence, employment, promotion, layoff and termination of employment.
-
Senior Research Scientist
5 days ago
Cambridge, Massachusetts, United States Massachusetts General Hospital Full timeJob Title: Senior Research ScientistJob Summary:The Massachusetts General Hospital is seeking a highly skilled Senior Research Scientist to join our Medical Device Plug-and-Play Interoperability and Cybersecurity (MD PnP) Program. As a key member of our team, you will play a critical role in advancing the development of next-generation medical systems and...
-
Cambridge, United States UCB Full time Make your mark for patients To strengthen our Discovery Sciences and Protein Sciences teams in our Boston hub in Cambridge, MA, USA, we are looking for a talented individual to fill the position of: Scientist or Senior Scientist. As (Senior) Scientist, you will contribute to a scientific team as protein biochemist and cellular biologist. You...
-
Senior Associate Scientist
2 months ago
Cambridge, United States Proclinical Staffing Full timeSenior Associate Scientist- Contract- Cambridge, MAProclinical is seeking a dedicated and detail-oriented Senior Associate Scientist to support stability and specification tasks for siRNA drug substances and drug products. Primary Responsibilities:The successful candidate requires a proactive individual who can manage specification change controls in a GMP...
-
Senior Research Scientist
4 weeks ago
Cambridge, Massachusetts, United States GC Therapeutics Full timeJob Title: Scientist/Senior ScientistGC Therapeutics is seeking a highly motivated and experienced Scientist/Senior Scientist to support the qualification and validation of assays for the testing, characterization, and release of novel Pluripotent Stem Cell (PSC) derived products.Key Responsibilities:Design, develop, and validate assays for testing the...
-
Senior Scientist, Immunology Discovery
6 days ago
Cambridge, United States Simcere Zaiming Full timeSenior Scientist (Preclinical-Autoimmunity)Simcere is seeking a Senior Scientist to join our preclinical team to help advance our discovery programs evaluating novel immune regulatory therapies to treat autoimmune and inflammatory diseases. The successful applicant will have a strong background and track record in designing, executing, analyzing, and...
-
Senior Scientist, Immunology Discovery
1 week ago
Cambridge, United States Simcere Zaiming Full timeSenior Scientist (Preclinical-Autoimmunity)Simcere is seeking a Senior Scientist to join our preclinical team to help advance our discovery programs evaluating novel immune regulatory therapies to treat autoimmune and inflammatory diseases. The successful applicant will have a strong background and track record in designing, executing, analyzing, and...
-
Senior Scientist, Immunology Discovery
1 week ago
Cambridge, United States Simcere Zaiming Full timeSenior Scientist (Preclinical-Autoimmunity)Simcere is seeking a Senior Scientist to join our preclinical team to help advance our discovery programs evaluating novel immune regulatory therapies to treat autoimmune and inflammatory diseases. The successful applicant will have a strong background and track record in designing, executing, analyzing, and...
-
Senior Scientist, Immunology Discovery
2 days ago
Cambridge, United States Simcere Zaiming Full timeSenior Scientist (Preclinical-Autoimmunity)Simcere is seeking a Senior Scientist to join our preclinical team to help advance our discovery programs evaluating novel immune regulatory therapies to treat autoimmune and inflammatory diseases. The successful applicant will have a strong background and track record in designing, executing, analyzing, and...
-
Senior Scientist, Immunology Discovery
1 day ago
Cambridge, United States Simcere Zaiming Full timeSenior Scientist (Preclinical-Autoimmunity)Simcere is seeking a Senior Scientist to join our preclinical team to help advance our discovery programs evaluating novel immune regulatory therapies to treat autoimmune and inflammatory diseases. The successful applicant will have a strong background and track record in designing, executing, analyzing, and...
-
Senior Associate Scientist
3 weeks ago
Cambridge, Massachusetts, United States Proclinical Staffing Full timeSenior Associate Scientist OpportunityProclinical Staffing is seeking a highly skilled and detail-oriented Senior Associate Scientist to support stability and specification tasks for siRNA drug substances and drug products in a GMP setting.Key Responsibilities:Manage specification change controls in a GMP environment.Contribute to general laboratory...
-
Senior Research Scientist
3 weeks ago
Cambridge, Massachusetts, United States GC Therapeutics Full timeJob Title: Senior Research ScientistGC Therapeutics is seeking a highly motivated and experienced Senior Research Scientist to join our neuroscience program. As a key member of our research team, you will be responsible for designing and executing preclinical in vivo studies to assess the efficacy of our cell therapies in small animal models of disease.Key...
-
Senior Clinical Safety Scientist
1 week ago
Cambridge, Massachusetts, United States Apnimed Full timeJob Title: Senior Clinical Safety ScientistApnimed is a clinical-stage pharmaceutical company dedicated to transforming the treatment of sleep apnea. We are seeking a highly skilled Senior Clinical Safety Scientist to join our team.Key Responsibilities:Analyze and summarize safety data from ongoing and completed studies to provide actionable insights and...
-
Senior Translational Data Scientist
3 weeks ago
Cambridge, Massachusetts, United States Bicycle Therapeutics Full timeJob Title: Senior Translational Data ScientistJob SummaryBicycle Therapeutics is seeking a highly skilled Senior Translational Data Scientist to join our Translational Sciences team. As a key member of our team, you will be responsible for leading the development, customization, and maintenance of a biomarker software solution to support our clinical-stage...
-
Senior Translational Data Scientist
1 month ago
Cambridge, Massachusetts, United States Bicycle Therapeutics Full timeJob DescriptionWe are seeking a highly skilled Senior Translational Data Scientist to join our Translational Sciences team at Bicycle Therapeutics. This individual will be responsible for leading the development, customization, and maintenance of a biomarker software solution to support our clinical-stage oncology portfolio assets.Key Responsibilities:Lead...
-
Senior Research Scientist
1 month ago
Cambridge, Massachusetts, United States AbbVie Full timeAbout the RoleWe are seeking a highly motivated and experienced Senior Scientist to join our Molecular Profiling and Drug Delivery (MPDD) team at AbbVie. As a Senior Scientist, you will play a key role in leading CMC developability assessment for emerging molecules on small molecule pipeline programs.Key ResponsibilitiesLead CMC developability assessment for...
-
Scientist/Senior Scientist
3 weeks ago
Cambridge, United States GC Therapeutics Full timeScientist/Senior Scientist - In Vivo Biology (Neuroscience)Company OverviewGC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome™ was developed in...
-
Senior Clinical Safety Scientist
3 weeks ago
Cambridge, Massachusetts, United States Apnimed Full timeJob Title: Senior Clinical Safety ScientistApnimed is a clinical-stage pharmaceutical company dedicated to transforming the treatment of sleep apnea. We are seeking a highly skilled Senior Clinical Safety Scientist to join our team.Job Summary:The Senior Clinical Safety Scientist will play a critical role in the Clinical Development and Safety teams,...
-
Senior Clinical Safety Scientist
6 days ago
Cambridge, Massachusetts, United States Apnimed Full timeJob Title: Senior Clinical Safety ScientistApnimed is a clinical-stage pharmaceutical company dedicated to transforming the treatment of sleep apnea. We are seeking a highly skilled Senior Clinical Safety Scientist to join our team.Job Summary:The Senior Clinical Safety Scientist will play a critical role in the Clinical Development and Safety teams,...
-
Cambridge, United States Third Rock Ventures Full timeAssociate Scientist/Scientist, In vivo pharmacologyA well-funded and highly innovative start up from Third Rock Ventures is emerging out of stealth with a syndicate of marquee investors and is seeking a talented Associate Scientist/Scientist to join the Biology-In vivo pharmacology team. The Associate Scientist/Scientist will serve as the in vivo...
-
Cambridge, United States Third Rock Ventures Full timeAssociate Scientist/Scientist, In vivo pharmacologyA well-funded and highly innovative start up from Third Rock Ventures is emerging out of stealth with a syndicate of marquee investors and is seeking a talented Associate Scientist/Scientist to join the Biology-In vivo pharmacology team. The Associate Scientist/Scientist will serve as the in vivo...
