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Senior Research Associate, Neurogenetics and Autism Research

4 weeks ago


Dallas, United States UT Southwestern Full time

Job Summary

Izumi lab is a translational genetic research laboratory. The research targets of Izumi lab are rare pediatric genetic disorders/autism diagnoses such as CHOPS syndrome and CBX1-related syndrome, and we use patient-derived samples and mouse models of these diagnoses for molecular investigation. Using cutting-edge genomic technologies, we hope to understand the disease mechanism of genetic disorders with the ultimate goal of identifying therapeutic strategies ameliorating clinical symptoms of these diagnoses.

Izumi lab is looking for a wet-bench Senior Research Associate with molecular biology experiment experience (more than 5 years). Induced pluripotent stem cell (iPSC) culture/neuronal differentiation experience and experience of handing research animals (mouse) are required.

This position is also expected to be involved in lab management work such as sample coordination and interactions with an institutional review board.

Laboratory Expectations

·Cell/tissue culture (mainly induced pluripotent stem cells)

·Mouse husbandry/colony maintenance

·Basic molecular biology experiments

oPCR, DNA extraction

oRNA extraction

oimmunoblotting

oqPCR

odroplet digital PCR

oDNA/RNA fluorescent in situ hybridization(FISH)

oCRISPR-Cas9 genome editing

oimmunohistochemistry staining

Experience and Education

·Ph.D. degree with major coursework in field of assignment and no experience required. or

·Master’s degree with major coursework in field of assignment and five (5) years laboratory experience, including at least two (2) years at level of Research Associate or equivalent. or

·Bachelor’s degree with major coursework in field of assignment and six (6) years laboratory experience, including at least two (2) years at level of Research Associate or equivalent.

Job Duties

·Organizes laboratory to which assigned; determines work assignments of subordinates, advising them as to techniques, procedures, and equipment to be utilized in solution of work problems; and reviews completed work for professional quality and attainment of desired results.

·Compiles and evaluates research data; develops new or revised techniques and procedures based upon such data.

·Performs or supervises design, development, or adaptation of equipment or apparatus used in research experiments to obtain desired results.

·Compiles and analyzes results of research assignments and submits to principal investigator.

·Instructs medical students, graduate students, residents, and other laboratory personnel of lower grade with respect to techniques, procedures, and equipment utilized in research or experiments.

·Confers with industrial, governmental, or other professional groups with respect to progress or results of research assignment.

·Assists principal investigator and other professional personnel in preparation of reports and papers for publication, usually exercising responsibility for writing of particular segment or phase of report or paper.

·Performs other duties as assigned.

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UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community.As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.