Research Scientist in Medicinal Chemistry

2 weeks ago


Durham, North Carolina, United States RTI International Full time

Position Overview:

The medicinal chemistry division at RTI International is dedicated to fulfilling client requirements through comprehensive hit-to-lead and lead optimization processes. Our team integrates medicinal chemistry within broader projects aimed at drug discovery and development, encompassing computational chemistry, in vitro assay development, high-throughput screening (HTS), in vivo behavioral pharmacology, ADME/PK bioanalytics, and regulatory assistance.

We are currently seeking a highly motivated and organized Research Scientist in Medicinal Chemistry to contribute to our dynamic and expanding team. The ideal candidate will be engaged in the synthesis of small molecules serving as ligands for diverse biological targets, including kinases, G protein-coupled receptors, ion channels, and antimicrobial agents.

At RTI International, you will have the opportunity to engage in impactful work within a collaborative, cross-functional setting. We prioritize your professional growth and offer a comprehensive benefits package that includes tuition reimbursement, parental leave, paid time off, medical and dental coverage, and a 401K plan.

Key Responsibilities:

  • Assist in the design of experiments.
  • Conduct compound synthesis independently or collaboratively.
  • Ensure meticulous execution of studies and maintain accurate records.
  • Perform data analysis and prepare manuscripts for publication.
  • Participate in conferences to present innovative research findings.
  • Support grant application processes.
  • Provide training to junior researchers and technicians as necessary.
  • Review scientific literature and patents to gather relevant information.
  • Undertake additional tasks as assigned by the Principal Investigator.

Qualifications:

  • Ph.D. in synthetic or medicinal chemistry or a closely related field.
  • Proficient in a broad range of chemical reactions.
  • Experience with LC/MS, NMR, and chiral separation techniques.
  • Familiarity with cell cultures and/or biological assays is highly desirable.
  • Basic knowledge of computational techniques is preferred.
  • Ability to work independently in a fast-paced environment.
  • Proficiency in English is required.

RTI International is committed to fostering innovation, developing talent, and promoting inclusivity. If these values resonate with you, we encourage you to consider this opportunity.

Compensation and Benefits:
The anticipated salary range for this position is between $52,000 and $65,000. RTI International offers a competitive total rewards package, including a base salary, generous paid time off, merit-based annual increases, bonus opportunities, and a robust recognition program. Additional benefits encompass a variety of insurance plans, access to retirement savings programs, paid parental leave, financial assistance for adoption or infertility treatments, and support for educational and developmental pursuits.



  • Durham, North Carolina, United States RTI International Full time

    Position Overview:The medicinal chemistry division at RTI International is dedicated to fulfilling client requirements through comprehensive hit-to-lead and lead optimization processes. Our team integrates medicinal chemistry with broader initiatives aimed at drug discovery and development, encompassing computational chemistry, in vitro assay development,...

  • Research Scientist

    2 days ago


    Durham, North Carolina, United States TalentBurst, an Inc 5000 company Full time

    Job Title: Research ScientistTalentBurst, an Inc 5000 company, is seeking a highly skilled Research Scientist to join our team in the department of Bioanalytics located in Research Triangle Park, NC.Job Summary:We are looking for a talented Research Scientist to conduct testing of samples in support of process development, characterization, developmental...


  • Durham, North Carolina, United States RTI International Full time

    About the RoleWe are seeking a highly motivated and talented Chemical Research Scientist to join our Advanced Materials & Environment team at RTI International. As a key member of our team, you will contribute to the development of novel materials, sorbents, and catalysts for various applications related to Energy.Key ResponsibilitiesDesign and Development:...


  • Durham, North Carolina, United States Aurobindo Pharma USA Full time

    Job SummaryAurobindo Pharma USA is seeking a highly skilled Chemist to join our team in a laboratory setting. As a key member of our research and development team, you will be responsible for conducting various stages of manufacturing using wet chemistry, physical, and instrumental techniques.Key Responsibilities:Perform testing of topical, transdermal, and...

  • Research Scientist

    1 day ago


    Durham, North Carolina, United States Compunnel Inc. Full time

    Job Title: Associate ScientistLocation: Durham, NCDuration: 6+ monthsSchedule: Monday to Friday 8:00 AM to 5:00 PMNo. of Openings: 1Job Description:Responsibilities:The successful candidate will be a recent graduate with a BS degree in Biology, Chemistry, or a related field.They will be responsible for maintaining and completing accurate records.Operate...

  • Materials Scientist

    5 days ago


    Durham, North Carolina, United States RTI International Full time

    About the RoleWe are seeking a highly motivated and talented Chemical Research Scientist to join our Advanced Materials & Environment team at RTI International. As a member of our team, you will have the opportunity to work on high-impact problems in applied chemistry and contribute to the development of novel materials, sorbents, and catalysts for different...


  • Durham, North Carolina, United States Jacobs Full time

    Your Contribution:Innovating Today. Shaping Tomorrow.At Jacobs, we are committed to your growth and success. Our endeavors extend beyond mere projects; they represent our shared human challenges. This is why we adopt a thoughtful and collaborative approach in every partnership.We strive to challenge conventional methods and redefine solutions to the world's...


  • Durham, North Carolina, United States Jacobs Full time

    Your Contribution:Innovating Today. Shaping Tomorrow.At Jacobs, we are committed to your growth and success. Our work transcends mere projects; it embodies our shared human endeavor. This is why we adopt a thoughtful and collaborative approach in every partnership.We challenge conventional thinking and redefine solutions to address the world's most pressing...


  • Durham, North Carolina, United States Jacobs Full time

    Your Contribution:Innovating Today. Shaping Tomorrow.At Jacobs, we are committed to your growth and success. Our endeavors extend beyond mere projects; they represent our collective challenge as human beings. We adopt a thoughtful and collaborative approach in every partnership we forge.We strive to challenge conventional methods and redefine solutions to...

  • Research Scientist II

    2 weeks ago


    Durham, North Carolina, United States Jacobs Full time

    Your Contribution:Innovating Today. Shaping Tomorrow.At Jacobs, we are committed to your growth and success. Our projects are not just tasks; they represent our collective challenge as innovators. We embrace a collaborative mindset in every partnership we forge.We are dedicated to challenging conventional methods and reimagining solutions to address the...


  • Durham, North Carolina, United States Jacobs Full time

    Your Contribution:Innovating Today. Shaping Tomorrow.At Jacobs, we are committed to your growth and success. Our work transcends mere projects; it embodies our collective challenge as human beings. This is why we adopt a thoughtful and collaborative approach in every partnership.We strive to challenge conventional methods and redefine solutions to the...


  • Durham, North Carolina, United States Teledyne Scientific & Imaging, LLC Full time

    Position Overview: Senior Research Scientist at Teledyne Scientific & Imaging, LLCTeledyne Scientific & Imaging, LLC is at the forefront of innovative research and technological advancements, boasting over five decades of expertise. We are in search of a proficient Senior Research Scientist to enhance our Intelligent Systems Laboratory, focusing on...

  • Senior Scientist

    2 months ago


    Durham, North Carolina, United States Alcami Corporation Full time

    Job Summary:The Senior Scientist - BioSeparations & Mass Spectrometry is the Subject Matter Expert (SME) for their field, demonstrates in depth working knowledge of scientific principles and leads the implementation of new methods/processes to solve problems. A Senior Scientist - BioSeparations & Mass Spectrometry will demonstrate expertise in Reversed...


  • Durham, North Carolina, United States Teledyne Scientific & Imaging, LLC Full time

    Senior Research Scientist Opportunity at Teledyne Scientific & Imaging, LLCTeledyne Scientific & Imaging, LLC is at the forefront of innovative research and technological advancements, boasting over five decades of expertise. We are on the lookout for a skilled Senior Research Scientist to contribute to our Intelligent Systems Laboratory, focusing on areas...


  • Durham, North Carolina, United States Teledyne Scientific & Imaging, LLC Full time

    Senior Research Scientist Opportunity at Teledyne Scientific & Imaging, LLCTeledyne Scientific & Imaging, LLC is at the forefront of pioneering research and technological innovation, boasting over five decades of expertise. We are in search of a distinguished Senior Research Scientist to enhance our Intelligent Systems Laboratory, focusing on areas such as...


  • Durham, North Carolina, United States BioAgilytix Full time

    About BioAgilytix: At BioAgilytix, we are dedicated to exceptional science and its transformative impact on healthcare. Our team comprises highly skilled scientists and professionals who provide customized services to support groundbreaking advancements in medicine through top-tier bioanalytical services. We pride ourselves on being solution-focused and...


  • Durham, North Carolina, United States Cambrex Full time

    About the RoleCambrex is seeking a highly skilled Senior Analytical Scientist to join our team. As a key member of our analytical department, you will be responsible for executing analytical methods, providing general analytical support, and leading a team of analytical chemists.Key ResponsibilitiesExecute analytical methods for in-process control, release...


  • Durham, North Carolina, United States PharmiWeb Global Life Science Jobs Full time

    About the RoleWe are seeking a highly skilled and experienced Senior Analytical Scientist to join our team at PharmiWeb Global Life Science Jobs. As a key member of our analytical team, you will be responsible for executing analytical methods and providing general analytical support, including release and stability testing of drug substances and drug...

  • Principal Scientist

    5 days ago


    Durham, North Carolina, United States Cambrex High Point Full time

    About the RoleCambrex High Point is seeking a highly skilled Senior Analytical Scientist to join our team. As a key member of our analytical department, you will be responsible for executing analytical methods, providing general analytical support, and leading cross-functional initiatives.Key ResponsibilitiesExecute analytical methods for in-process control,...


  • Durham, North Carolina, United States Biomason, Inc. Full time

    Job OverviewCompany Background: Biomason, Inc. is at the forefront of revolutionizing the construction industry by utilizing biological processes to create sustainable cement alternatives. Our mission is to lead the transition towards environmentally friendly building materials, addressing the critical challenge of climate change. We are dedicated to...