Associate Director, Computational Immunology Expert

4 weeks ago


Boston, Massachusetts, United States Tempus Full time
Lead Computational Immunology Research

Tempus is seeking a highly skilled Associate Director of Computational Immunology to lead and oversee projects leveraging our multi-modal database to support specific biopharmaceutical partners in advancing their drug discovery portfolio, with a focus on immuno-oncology.

Key Responsibilities:
  • Design and implement research studies, analyzing data, reviewing methods, and providing actionable insights to guide discovery or decision-making to improve outcomes for biopharma.
  • Lead a dynamic team of computational scientists executing Translational or Real-World Evidence projects integrating molecular and clinical data from Tempus' multimodal data platform to derive insights for biopharma partners.
  • Establish best practices for reproducibility, help identify analytical gaps, and suggest next steps.
  • Work closely with internal teams, including key account directors, business development, operations, alliance management, and research informatics, to align team initiatives with broader business goals.
  • Oversee the generation of contracted deliverables and executive summaries for biopharma customers.
Requirements:
  • PhD degree in a quantitative discipline (e.g. Computational Biology, Cancer Biology, Computational Immunology, Biostatistics/Statistical Genetics, Bioinformatics, or similar).
  • Minimum 4+ years in drug development leveraging genomic and multimodal data for drug discovery and development.
  • Proficient in R, Python, and SQL. Strong understanding of Cancer, Immunology, Clinical Trials, and Real-World Evidence Platforms.
  • Extensive prior experience analyzing genomic data, including whole exome sequencing, whole transcriptome sequencing, TCR/BCR immune repertoire sequencing, and particularly single-cell RNA sequencing.
Preferred Skills:
  • Strong understanding of molecular data and artificial intelligence in drug discovery with experience in integrative modeling of multi-modal clinical and omics data.
  • Previous experience working with large clinical datasets (EHR, claims data, clinical trials, patient registries, etc)
  • Previous experience working with large transcriptome and NGS data sets.
  • Experience in cancer immunology and TCR-seq

Tempus is an equal opportunity employer and does not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.



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