Senior Director, Precision Medicine Analytics

3 weeks ago

Cambridge, Massachusetts, United States Sarepta Therapeutics Full time

About the Role:

The Associate Director, Commercial Diagnostics & Bioinformatics at Sarepta Therapeutics plays a crucial role in driving the strategic vision and objectives to make the company a recognized leader in precision genetic medicine for rare diseases.

This highly engaging hands-on role requires the integration of technical expertise in genetic data analytics and data integration with the ability to understand commercial insights.

The ideal candidate will analyze genetic diagnostic data to provide insights and guidance for the development of potential commercial activities and decision making. Success in this role is dependent upon technical/coding expertise, interpretation of data, commercial knowledge, effective collaboration with cross-functional departments, and proficiency working in a global matrix environment.

Key Responsibilities:

  • Contribute to the development, execution, and management of a Commercial Diagnostic Data strategy
  • Oversee and contribute to genetic and/or other diagnostic data ingestion and reporting processes
  • Conceive, design, perform, and deliver ad-hoc and pre-specified genetic data analyses, develop insights, and recommendations for internal stakeholders
  • Identify new data sources/vendors, determine contract requirements, manage contract negotiations, direct day-to-day activities, and contribute to building new data models
  • Oversee and refine genetic diagnostic data pipeline ingestion, QC, and processing; monitor the audit process to maintain data integrity and ensure quality data sets; remediate genetic diagnostic data quality issues with multiple external vendors in a timely manner
  • Develop and implement governance guidelines in conjunction with cross-functional partners; provide oversight to ensure that genetic diagnostic data are used appropriately within the organization
  • Collaborate with cross-functional partners to leverage available genetic databases for ad-hoc analyses to answer commercially focused questions
  • Drive innovation by embracing a 'connect the dots' mindset, initiative-taking identification, and dissemination of actionable biological information
  • Effectively communicate and present analysis results to collaborators and help drive decision-making
  • Partner to create data visualizations in Tableau, Shiny, and/or other dashboarding tools; assess initial validity and monitor accuracy of dashboards
  • Maintain knowledge based on the latest relevant scientific literature to identify and evaluate state-of-the-art methodologies and strengthen the team capabilities
  • Support the development of educational materials for commercial activities

Requirements:

  • PhD in Genetics with a focus in Bioinformatics, or related degree in Life Sciences; MBA a plus
  • 10+ years of relevant experience in the biopharmaceutical industry focusing on translational research, genetic analyses
  • Experience with genetic variant interpretation in the context of ACMG (American College of Medical Genetics) classification, familiarity with genetic variant types and formats (e.g., HGVS), and data analyses of large genetic data sets
  • Ability to convey potentially complex and technical analysis in simple terms to non-technical audiences
  • Intermediate/Advanced Python programming and experience in Unix/Linux environment
  • Proficiency in Tableau, PowerBI, R/R Shiny, and/or other dashboarding tools strongly preferred
  • Ability to work with relational databases (SQL experience preferred)
  • Ability to work in a shared coding environment while adhering to best coding and software development practices in both development and production environments
  • Demonstrated ability to manage multiple complex projects and programs simultaneously
  • Positive, open, and creative attitude with strong collaboration, interpersonal, and communication skills with cross-functional partners
  • Ability to travel up to 15%

About Sarepta Therapeutics:

Sarepta Therapeutics is a leader in precision genetic medicine for rare diseases. We're committed to making a difference in the lives of patients and their families. If you're comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.

What We Offer:

Sarepta Therapeutics offers a competitive compensation and benefit package, including a targeted salary range of $156,000 - $195,000 per year. We're an Equal Opportunity/Affirmative Action employer and participate in e-Verify.

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