Senior Director of Clinical Research
4 weeks ago
The Senior Director of Clinical Research will lead the development of first-in-man, proof-of-mechanism, and proof-of-concept studies for novel biological and small molecule therapies in respiratory disease programs.
Key Responsibilities- Develop disease-specific global networks of investigators and key opinion leaders for trial design, management, and recruitment.
- Design and implement proof-of-mechanism, proof-of-concept, and dose-ranging studies in collaboration with Pfizer development operations and project teams.
- Develop primary and secondary endpoints for efficacy and safety, and contribute to precision medicine and biomarker strategies.
- Provide leadership in the preparation of critical documents, including clinical protocols, development plans, and regulatory documents.
- Collaborate with cross-functional teams, including biostatistics, clinical pharmacology, and regulatory affairs, to ensure seamless transition of assets to late-stage development.
- MD or MD/PhD degree with a pulmonary specialty required.
- Five or more years of experience in biopharmaceutical-sponsored clinical research, with a minimum of two years in respiratory area.
- Experience as a medical monitor and clinical lead across therapeutic areas is desirable.
- Good understanding of biostatistics, regulatory, clinical pharmacology, pre-clinical toxicology, pharmacogenomics, and biomarker-based approaches.
Pfizer offers a comprehensive benefits package, including a 401(k) plan, paid vacation, holiday, and personal days, paid caregiver/parental and medical leave, and health benefits.
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Senior Director of Clinical Operations
4 weeks ago
Cambridge, Massachusetts, United States Akebia Therapeutics Full timeJob DescriptionJob Title: Senior Director, Clinical OperationsCompany: Akebia TherapeuticsJob SummaryAkebia Therapeutics is seeking a highly experienced Senior Director, Clinical Operations to lead our clinical development programs. The successful candidate will have a strong background in clinical trial management, with a proven track record of delivering...
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Cambridge, Massachusetts, United States ICON Strategic Solutions Full timeJob Title: Sr. CRA**Job Summary:**We are seeking a highly skilled and experienced Senior Clinical Research Associate (CRA) to join our Clinical Operations team at ICON Strategic Solutions. The successful candidate will be responsible for providing leadership in the execution of clinical studies, ensuring high-quality data is delivered to sponsors on time,...
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Senior Manager, Clinical Researcher
4 weeks ago
Cambridge, Massachusetts, United States Moderna Therapeutics Full timeKey ResponsibilitiesThe Senior Manager, Clinical Researcher will support the development of early and late phase Oncology Vaccine programs. This role will collaborate with the Study Physician to oversee clinical studies, review and interpret clinical trial data, and execute deliverables in collaboration with internal and external partners.The Clinical...
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Cambridge, Massachusetts, United States Biogen Idec Full timeAbout This RoleAs a pivotal leader within Biogen, the Senior Medical Director, Clinical Development and Movement Disorders Lead will spearhead clinical development strategies and provide medical expertise across our movement disorders portfolio, including business development with a focus on the future portfolio. This role is situated within the Therapeutics...
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Veterinarian Researcher
3 weeks ago
Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full timeJob Title: Research/Clinical VeterinarianDivision: Division of Comparative MedicineJob Summary: We are seeking a Research/Clinical Veterinarian to join our team at the Massachusetts Institute of Technology. The successful candidate will provide broad clinical veterinary support across multiple facilities for multiple small and large animal species, depending...
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Senior Director of Clinical Development
4 weeks ago
Cambridge, Massachusetts, United States Alkeus Pharmaceuticals, Inc. Full timeAbout Alkeus PharmaceuticalsAlkeus Pharmaceuticals, Inc. is a late-stage biopharmaceutical company dedicated to developing innovative therapeutics for serious, progressive eye diseases that lead to blindness. Our lead compound, gildeuretinol (ALK-001), is an oral investigational drug being developed for the treatment of Stargardt disease (STGD) and...
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Senior Research Scientist
4 weeks ago
Cambridge, Massachusetts, United States Mass General Brigham Full timeJob SummaryWe are seeking a highly skilled Senior Research Scientist to join our team at Mass General Brigham. As a key member of our research team, you will be responsible for leading research projects and collaborating with cross-functional teams to develop innovative solutions for medical device interoperability and cybersecurity.Key Responsibilities:Lead...
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Oncology Research Director
4 weeks ago
Cambridge, Massachusetts, United States Flagship Ventures Full timeAbout the Role:We are seeking a highly motivated and experienced Associate Director/Director Oncology to join our team at Quotient Therapeutics, Inc. in Cambridge, MA. As a key member of our precision oncology research team, you will play a vital role in advancing our lead candidates to IND and early clinical studies.Key Responsibilities:Design, plan, and...
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Clinical Sciences Associate Director
4 weeks ago
Cambridge, Massachusetts, United States Novartis Pharmaceuticals Full timeJob Summary:We are seeking a highly skilled Clinical Sciences Associate Director to lead our global clinical trials in oncology and hematology. As a key member of our research team, you will be responsible for driving the development of new treatments and therapies.Key Responsibilities:Lead cross-functional teams to design and execute clinical trials,...
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Cambridge, Massachusetts, United States Moderna Full timeAbout the RoleModerna is seeking a highly skilled and strategic Director of Shared Antigen Cancer Vaccines Research to join our Cancer Vaccines Research team, focusing on early pipeline programs. The Director will lead the early discovery and preclinical validation of shared antigen cancer vaccine candidates, overseeing the translation of innovative...
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Senior Research Scientist
4 weeks ago
Cambridge, Massachusetts, United States Mass General Brigham Full timeJob SummaryWe are seeking a highly skilled Senior Research Scientist to join our team at Mass General Brigham. The successful candidate will have a strong background in medical device interoperability and cybersecurity, with a proven track record of leading research projects and managing technical staff.Key ResponsibilitiesResearch and Development: The...
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Senior Director of Business Development
1 month ago
Cambridge, Massachusetts, United States Simcere Full timeJoin Simcere Pharmaceutical Group as a Senior Director of Business DevelopmentSimcere Pharmaceutical Group is a pioneering pharmaceutical company driven by innovative research and development. Our mission is to provide patients with cutting-edge medicines across key therapeutic areas, including oncology, central nervous system, autoimmunity, and infectious...
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Senior Director of Translational Medicine
4 weeks ago
Cambridge, Massachusetts, United States Astellas Pharma Full timeJob SummaryThe Senior Director of Translational Medicine will lead the development and implementation of the Translational Medicine strategy within a defined disease or primary focus area. This position is responsible for developing the translational strategies for Astellas assets, taking accountability for day-to-day delivery aligned with approved...
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Cambridge, Massachusetts, United States Takeda Full timeJob SummaryWe are seeking a highly experienced Medical Director to lead our clinical development efforts in the Neuroscience Therapeutic Area. As a key member of our team, you will be responsible for driving strategy and decision-making for our pipeline compounds, working closely with cross-functional teams to ensure successful development and regulatory...
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Clinical Research Nurse
4 weeks ago
Cambridge, Massachusetts, United States Mass General Brigham Full timeAbout the RoleMass General Brigham is seeking a highly skilled Clinical Research Nurse to join our team. As a key member of our research team, you will be responsible for implementing and conducting clinical trials in various disease programs.Key ResponsibilitiesCollaborate with physicians and research teams to establish processes and workflows for protocol...
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Clinical Research Nurse
4 weeks ago
Cambridge, Massachusetts, United States Mass General Brigham Full timeJob SummaryMass General Brigham is seeking a highly skilled Clinical Research Nurse to join our team. As a key member of our research team, you will be responsible for implementing and conducting clinical trials in various disease programs.Key Responsibilities:Collaborate with physicians and research teams to establish processes and workflows for protocol...
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Senior Finance and Operations Manager
4 weeks ago
Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full timeJob Title: Senior Finance and Operations ManagerJob Summary:We are seeking a highly skilled Senior Finance and Operations Manager to join our team at the Abdul Latif Jameel Poverty Action Lab (J-PAL). The successful candidate will be responsible for supporting J-PAL's mission to efficiently translate research into actionable poverty alleviation policies...
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Senior Finance and Operations Manager
4 weeks ago
Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full timeJob SummaryAbdul Latif Jameel Poverty Action Lab (J-PAL) is seeking a Senior Finance and Operations Manager to support its mission to efficiently translate research into actionable poverty alleviation policies. The successful candidate will work under the supervision of the director of finance and operations and serve as financial and operational lead for a...
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Director of Metabolic Disease Discovery Research
4 weeks ago
Cambridge, Massachusetts, United States Flagship Pioneering, Inc. Full timeTransforming Human Health: Flagship Pioneering, Inc. is seeking a highly motivated and experienced Director in Metabolic Disease Discovery Research to join our team. As a key member of our research team, you will play a vital role in progressing lead candidates to IND and early clinical studies. Your expertise in pharmacology and physiology will be...
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Senior Finance and Operations Manager
4 weeks ago
Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full timeJob Title: Senior Finance and Operations ManagerJob Summary:We are seeking a highly skilled Senior Finance and Operations Manager to join our team at the Abdul Latif Jameel Poverty Action Lab (J-PAL). The successful candidate will support J-PAL's mission to efficiently translate research into actionable poverty alleviation policies around the world.Key...