Director, DMPK Program Lead

1 month ago

Palo Alto, California, United States Evommune, Inc. Full time
Job Title: Director, DMPK

Evommune, Inc. is seeking a highly motivated and dynamic Director, DMPK to join our innovative biotech start-up. As a key member of our R&D team, you will provide technical and scientific leadership in establishing ADME/PK/PK-PD strategies for discovery and development programs with small molecules.

Key Responsibilities:
  • Develop and implement DMPK and PK-PD strategies to support timely selection and development of small molecules.
  • Collaborate with multiple R&D functional areas to support DMPK needs, enabling decision making for advancement of projects.
  • Design, oversee, and analyze DMPK studies while timely communicating study results to project teams and senior management.
  • Manage contract research organizations (CROs)/vendors and consultants.
  • Be responsible for or author PK sections of regulatory submissions and respond to questions from regulatory agencies.
Requirements:
  • PhD in PK, drug metabolism, or a related discipline with at least 10 years of relevant industry experience or equivalent experience based on training and experience.
  • Experience with clinical candidate selection and development of small molecules, design/conduct of experiments to understand drug disposition profiles and PK-PD relationships, and first-in-human dose projections.
  • Ability to oversee bioanalytical studies and support clinical pharmacology as needed.
  • Understanding of regulatory guidelines to support small molecule drug development.
  • Excellent written and interpersonal communications, and proven problem solving and analytical abilities.
What We Offer:
  • Competitive salary range of $190,000 to $250,000, with potential for performance-based bonuses and/or equity-linked compensation.
  • Company-sponsored benefits, including comprehensive health, dental, and vision plans, 401(k) plan, ample time off programs, paid parental leave, life insurance, disability insurance, and an employee referral bonus program.

Evommune, Inc. is an equal opportunity employer and welcomes applications from qualified candidates.

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