Professional Researcher
2 days ago
We are seeking a highly motivated and experienced Professional Researcher to join our team at the University of California, San Francisco. The successful candidate will be responsible for leading early-stage pre-clinical development of novel T cell therapeutic circuits for the treatment of Leiomyosarcoma.
Key Responsibilities
The ideal candidate will have a strong background in cellular biology, immunology, or a related field, with experience in T cell therapy development, CAR construct design, and cloning. They will be responsible for developing novel assays, designing and validating T cell circuits, establishing in-vivo tumor models, and compiling pre-clinical results to support clinical vector design. The candidate will also lead the in-vitro and in-vivo pharmacology characterization of therapeutic product candidates in collaboration with a process development team towards an IND filling.
Requirements
A doctorate or its equivalent with 2+ years related experience in cellular biology, immunology, or a related field. Experience with human and mouse T cell isolation and culture, T cell therapy development, and extensive understanding of techniques such as CAR construct design and cloning, viral vector development, T cell engineering, and CRISPR gene editing. The candidate must also have excellent attention to detail, organizational and interpersonal communication skills, and the ability to work independently and as a member of a research team.
Preferred Qualifications
A track record of independent research, history of potential to develop a sustained source of research funding, and completion of a post-doctoral fellowship. The candidate must also have a strong publication record and a proven ability to secure research funding.
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