Antibody Research Scientist

2 weeks ago


San Francisco, California, United States BEPC Inc. - Business Excellence Professional Consulting Full time

Join our team at BEPC Inc. - Business Excellence Professional Consulting

Antibody Research Associate II Position

About the Role:

We are seeking a highly motivated and experienced Scientist 2/3 to join our Antibody Engineering Department

The successful candidate will have a B.S. or M.S. degree in molecular biology or related science and 4+ years of applying molecular biology skills, preferably in an antibody research or industrial setting

Key Responsibilities:

  • Work with other scientists focused on discovery, developing, and engineering therapeutic antibody candidates
  • Apply molecular biology skills to drive the rapid assembly of antibody encoding plasmids for expression from mammalian cells
  • Collaborate in developing high throughput plasmid assembly solutions for various complex, and multi-specific antibody designs
  • Collaborate with automation engineers to build and develop workflows for high throughput, automated processes for DNA plasmid assembly and clonal mAb selection
  • Interact with informatic engineers to develop processes that support automated antibody development workflows including antibody (DNA and protein sequence) registration, tracking, archiving, and inventory

Requirements:

  • Basic understanding of antibody therapeutics including IgGs (variable heavy and light chains and constant region), FAbs, bispecific antibodies, and VHH antibodies
  • Experience and expertise in performing polymerase chain reactions (PCR), general DNA plasmid construct assembly, steps necessary for antibody clone isolation including bacterial transformation, bacterial colony picking, bacterial clone culturing, plasmid purification at the mini to maxi scale, and analyzing DNA sequences
  • Experience in working with tools for antibody DNA sequence analysis, sequence confirmation, and sequence alignment is essential
  • Basic molecular biology skills in DNA ligation, DNA mutagenesis, oligonucleotide design, and endonuclease restriction digestion analysis are also required
  • Experience with surface plasmon resonance (SPR), performing binding ELISAs and graphing is preferred
  • Must have excellent record keeping skills, strong communication skills, and be experienced in data management using Excel or Google Drive

What We Offer:

  • 1 year contract with possible extensions
  • Benefits include Medical, Dental, Vision, and Life Insurance
  • Pay Rate: $45.00-$48.61

Apply Now:



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