Senior Director of Oligonucleotide Biology
4 weeks ago
Simcere Pharmaceutical Group is a pioneering pharmaceutical company driven by cutting-edge R&D. We are committed to delivering groundbreaking medicines across core therapeutic areas, including oncology, CNS disorders, autoimmunity, and infectious diseases. Our Boston Innovation Center is dedicated to developing transformative technologies and medicines in oncology, CNS disorders, and autoimmune diseases.
We are seeking a collaborative and visionary leader to join our team. As Senior/Executive Director, you will be responsible for advancing groundbreaking modalities for the treatment of CNS diseases. Your expertise in oligonucleotide biology and RNA therapeutic drug development will be instrumental in shaping our portfolio strategy.
Key Responsibilities:- Lead the identification and mechanistic profiling of lead oligonucleotide compounds to provide high-value programs.
- Make strategic and quality decisions for programs in alignment with Simcere's management teams.
- Craft an innovative product profile and guide decision-making by formulating outcome scenarios at critical data inflection points.
- Assemble and maintain a motivated and high-performing program team, ensuring team members meet their expectations.
- Provide relevant input into other portfolio project teams when needed.
- Establish and cultivate cross-functional relationships with internal stakeholders.
- Provide oversight to collaborative programs and maintain strong relationships with investigators and key opinion leaders (KOLs) in the field.
- PhD, MD, or MD/PhD in neuroscience or related fields, with 6+ years of experience in oligonucleotide biology.
- Experience in leading a group to study RNA biology and function in academic or industrial settings.
- Expertise in RNA therapeutic drug development process is highly desirable.
- Excellent communication and negotiation abilities, along with prior experience in leading organizations and guiding individuals through transformative changes.
- Demonstrated success in building teams, leading, and influencing experienced professionals and executives.
- Ability to think critically, creatively, and to anticipate and solve problems.
-
Senior Scientist RNA Oligonucleotide Synthesis
1 month ago
Cambridge, Massachusetts, United States Beacon Hill Life Sciences - Boston Full timeJob SummaryWe are seeking a highly skilled Senior Scientist to join our RNA Chemistry Team. The successful candidate will be responsible for the synthesis, purification, and characterization of oligonucleotides.Key Responsibilities:Design and implement oligonucleotide synthesis and purification protocols.Operate and maintain automated oligo synthesizers and...
-
Senior Oligonucleotide Development Specialist
3 weeks ago
Cambridge, Massachusetts, United States Beacon Hill Life Sciences - Boston Full timeJob OverviewWe are seeking a highly skilled and experienced Senior Oligonucleotide Development Specialist to join our team at Beacon Hill Life Sciences in Boston.
-
Scientific Leader for Oligo Platform Biology
4 weeks ago
Cambridge, Massachusetts, United States GlaxoSmithKline, plc Full timeAs a key member of the GlaxoSmithKline, plc team, the Oligo Platform Biology Investigator/Science Leader will play a pivotal role in establishing and managing the company's new oligo platform biology lab. This individual will focus on enabling the identification and characterization of oligonucleotides to support portfolio and platform projects.Key...
-
Senior Director/Program Lead, Biology
4 weeks ago
Cambridge, Massachusetts, United States Fog pharma Full timeTransformative Opportunity in Oncology Drug DevelopmentAt FogPharma, we're pioneering the discovery and development of Helicon therapeutics, peptides capable of efficient cell entry and modulation of both protein-protein and protein-DNA interactions. As a Senior Director/Program Lead, Biology, you'll drive cell and translational biology for multiple oncology...
-
Cambridge, Massachusetts, United States Beacon Hill Life Sciences - Boston Full timeJob OverviewWe are seeking a highly skilled Research Associate to join our RNA Chemistry Team. The successful candidate will be responsible for the synthesis, purification, and characterization of oligonucleotides.Key Responsibilities:Operate and maintain oligonucleotide synthesis platforms and other scientific equipment.Develop and implement oligonucleotide...
-
Cambridge, Massachusetts, United States Beacon Hill Life Sciences - Boston Full timeJob SummaryWe are seeking a highly skilled and motivated Senior Research Scientist to join our Nucleic Acid Process Development team. The ideal candidate will have expertise in mRNA synthesis and characterization, as well as experience with oligonucleotide enzymatic and/or chemical synthesis.Key Responsibilities:Develop and optimize mRNA synthesis methods...
-
Senior Scientist, Biology Lead
4 weeks ago
Cambridge, Massachusetts, United States Crossbow Therapeutics, Inc Full timeAbout the OpportunityCrossbow Therapeutics, Inc. is a biotechnology company dedicated to revolutionizing cancer treatment through innovative immunotherapies. We are seeking a highly skilled Senior Scientist/Principal Scientist, Biology to join our dynamic team.Key Responsibilities:Lead programs from discovery through DC nomination, driving scientific rigor...
-
Senior/Principal Scientist, Biology
4 weeks ago
Cambridge, Massachusetts, United States Crossbow Therapeutics, Inc Full timeCrossbow Therapeutics, Inc. is a biotechnology company dedicated to improving the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. Our T-BoltTM therapies are next-generation, easily assembled immunotherapies directed with high precision at previously unreachable cancer cell targets. Our approach...
-
Senior Analytical Development Director, CMC
4 weeks ago
Cambridge, Massachusetts, United States Agios Pharmaceuticals Full timeRole SummaryAgios Pharmaceuticals is seeking a highly motivated Associate Director, Analytical Development, CMC to join our growing CMC team. The ideal candidate will be a key stakeholder within analytical development team to help build and lead the analytical development function within CMC and hands-on contributor to the overall CMC strategy of drug...
-
Analytical Development Director
3 weeks ago
Cambridge, Massachusetts, United States Agios Pharmaceuticals Full timeLead Analytical Development at Agios PharmaceuticalsAgios Pharmaceuticals is a biopharmaceutical company that empowers connections, fostering a supportive, fun, and flexible environment where employees thrive. We care deeply about our work, each other, and the patients who rely on us. We cultivate strong bonds with patient communities, healthcare...
-
Senior Analytical Development Manager, CMC
4 weeks ago
Cambridge, Massachusetts, United States Agios Pharmaceuticals Full timeJob Summary:We are seeking a highly motivated and experienced Senior Analytical Development Manager, CMC to join our growing CMC team at Agios Pharmaceuticals. The successful candidate will be responsible for leading the analytical development function within CMC and contributing to the overall CMC strategy of drug development at Agios.Key Responsibilities:...
-
Director of Discovery Biology
4 weeks ago
Cambridge, Massachusetts, United States Vesalius Therapeutics Full timeJob SummaryVesalius Therapeutics is seeking a highly experienced and motivated biologist to lead their drug discovery efforts. The ideal candidate should have a strong background in drug discovery and be passionate about leveraging the latest advances in biology, chemistry, and computation to develop new treatments for common diseases.Key...
-
Director of Chemistry
4 weeks ago
Cambridge, Massachusetts, United States Moderna Therapeutics Full timeAbout the RoleModerna Therapeutics is seeking a highly skilled Director-level chemist to lead our Discovery Chemistry group. As a key member of our team, you will be responsible for designing and synthesizing novel LNP components and oligonucleotides, driving multiple research projects across various therapeutic areas.Key ResponsibilitiesProvide strategic...
-
STEM Internship Opportunity in Synthetic Biology
4 weeks ago
Cambridge, Massachusetts, United States RevivBio Full timeJob Opportunity at RevivBioWe are seeking a highly motivated and detail-oriented intern to join our team at RevivBio, a venture-backed synthetic biology company located in Cambridge, MA.The ideal candidate will have a strong foundation in chemistry and the ability to apply analytical skills to solve complex problems. Experience with laboratory...
-
Senior/Principal Scientist, Biology
4 weeks ago
Cambridge, Massachusetts, United States Crossbow Therapeutics, Inc Full timeCrossbow Therapeutics, Inc. is a biotechnology company dedicated to improving the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies.The company's T-BoltTM therapies are next-generation, easily assembled immunotherapies directed with high precision at previously unreachable cancer cell targets. Our...
-
Senior Molecular Biology Research Associate
1 month ago
Cambridge, Massachusetts, United States Nanobiosym Full timeJoin Our Team of InnovatorsNanobiosym is revolutionizing personalized medicine, novel technologies, and healthcare delivery. As a renowned MIT and Harvard trained Physician and Physicist, our founder has pioneered a pipeline of products leveraging cutting-edge advances in physics, biomedicine, and nanotechnology. With multiple prestigious peer-reviewed...
-
RNA Chemical Biology Co-op Internship
4 weeks ago
Cambridge, Massachusetts, United States Moderna Full timeRole OverviewThis is a co-op internship opportunity in the field of chemical biology at Moderna. The individual will work at the Cambridge, MA site and focus on the chemical biology of nucleic acids and RNA biochemistry to develop Moderna's next generation building blocks for mRNA medicines. The co-op will be mentored by a Sr. Scientist and will design...
-
Academic Director
4 weeks ago
Cambridge, Massachusetts, United States Vesalius Therapeutics Full timeJob SummaryVesalius Therapeutics is seeking a highly experienced and motivated biologist to lead their drug discovery efforts as the Director, Discovery Biology. The ideal candidate should have a strong background in drug discovery and be passionate about leveraging the latest advances in biology, chemistry, and computation to develop new treatments for...
-
Cambridge, Massachusetts, United States Skills Alliance Full timeJob SummaryWe are seeking a highly motivated and passionate research associate to support drug discovery projects. The successful candidate will have a solid understanding of protein biochemistry and molecular biology, with experience in structural biology being advantageous.Key Responsibilities:Develop and execute strategies to clone and express recombinant...
-
STEM Internship Opportunity in Synthetic Biology
3 weeks ago
Cambridge, Massachusetts, United States RevivBio Full timeWe are seeking a highly motivated intern to join our multidisciplinary team at RevivBio, a venture-backed synthetic biology company located in Cambridge, MA.The successful applicant will have knowledge of chemistry and the ability to apply this knowledge analytically, as well as hands-on experience working in laboratory and laboratory instrumentation.The...