Principal Investigator, Biopharmaceutical Development
2 weeks ago
The Principal Research Investigator will lead the development of novel formulations and manufacturing processes for monoclonal antibodies and bispecific biologic products at Incyte Corporation.
Key Responsibilities- Conduct research to develop formulations, manufacturing processes, and primary container configurations for biologic products.
- Participate in drug product development teams and contribute to the planning and execution of product development studies.
- Design, execute, and interpret development studies based on defined project objectives.
- Manage CRO and CMO to generate high-quality data and summarize results in technical reports, scientific papers, and presentations.
- Interact effectively with members of the Global Biopharmaceutical Development department and cross-functional internal and external partners.
- Ph.D./M.Sc./B.S. in Pharmaceutical Sciences, Chemical Engineering, or relevant scientific discipline with a minimum of 8 years of relevant industrial experience in formulation and drug product development of therapeutic protein products.
- Scientific background and hands-on experience in protein formulation, biologic drug product process development for liquid and lyophilized products, and biophysical characterization of proteins.
- Experience in developing optimal formulations for biological products and establishing robust process conditions for manufacturing.
- Technical expertise in aspects of drug product development and/or manufacturing processes, including formulation, compounding, sterile processing, filling, lyophilization, and primary packaging.
- Understanding the relationships between formulation, manufacturing process, and device design for the performance, quality, and stability of biological drug products.
- Experience in statistical experimental design and data analysis, including Design of Experiments (DoE).
- Experience with process characterization, validation, risk assessment, and control strategies of protein drug products.
- Proven ability to work effectively in team structures and collaborate with cross-functional internal/external partners.
- Demonstrated ability for critical thinking, problem-solving, and creativity.
- Strong organizational and planning skills.
- Strong written and verbal communication skills, good interpersonal skills, ability to multi-task, publication track record, and a strong desire to learn, contribute, and collaborate.
Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.
-
Wilmington, Delaware, United States Incyte Full timeJob SummaryThe Principal Research Investigator will lead the development of novel formulations and manufacturing processes for monoclonal antibodies and bispecific biologic products at Incyte, a biopharmaceutical company dedicated to improving patient outcomes in oncology and inflammation and autoimmunity.Key ResponsibilitiesConduct research to develop...
-
Wilmington, Delaware, United States Incyte Full timeJob SummaryThe Principal Research Investigator will lead the development of novel formulations and manufacturing processes for monoclonal antibodies and bispecific biologic products. This role will be responsible for conducting research, designing and executing development studies, and collaborating with cross-functional teams to advance product...
-
Senior Principal Biostatistician
2 weeks ago
Wilmington, Delaware, United States Incyte Full timeJob SummaryThe Senior Principal Biostatistician is responsible for providing statistical support to drug development programs at Incyte, a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines.Key ResponsibilitiesInteract with multidisciplinary project teams to establish project timelines and provide...
-
Epic Principal Trainer
1 week ago
Wilmington, Delaware, United States MVP Consulting Inc Full timeJob Title: Epic Principal TrainerJob Summary:We are seeking an experienced Epic Principal Trainer to join our team at MVP Consulting Inc. As a key member of our training team, you will be responsible for developing and delivering high-quality training content to our clients.Key Responsibilities:Developing role-based training content using a variety of...
-
Wilmington, Delaware, United States Alamance County, NC Full timeJob Title: Deputy (Investigator) - Criminal Investigations DivisionJob Summary:We are seeking a highly skilled and motivated individual to join our team as a Deputy (Investigator) in the Criminal Investigations Division. As a Deputy, you will be responsible for conducting investigations, gathering evidence, and interviewing witnesses to solve crimes. You...
-
DCVPA Principal
4 weeks ago
Wilmington, Delaware, United States University of North Carolina Wilmington Full timeJob SummaryThe DCVPA Principal serves as the leader of the school, overseeing the development and implementation of policies, programs, curriculum activities, and budgets to promote the educational growth of each student and the professional development of each staff member.Key ResponsibilitiesChief Administrator for Operations: Building Management, Budget,...
-
DCVPA Principal
4 weeks ago
Wilmington, Delaware, United States University of North Carolina Wilmington Full timeJob SummaryThe DCVPA Principal is a key leadership position responsible for overseeing the academic and administrative operations of the DC Virgo Preparatory Academy. As a member of the University of North Carolina Wilmington community, this role requires a strong commitment to education, leadership, and collaboration.Key ResponsibilitiesDevelop and...
-
Analytical Development Expert
7 days ago
Wilmington, Delaware, United States Incyte Full timeCompany OverviewIncyte is a biopharmaceutical company that focuses on the discovery, development, and commercialization of novel medicines to address serious unmet medical needs in oncology and inflammation and autoimmunity.The company is committed to rigorous research and development excellence to improve the lives of patients, make a difference in...
-
Biostatistics Leader
2 weeks ago
Wilmington, Delaware, United States Al Solutions Full timePrincipal Biostatistician Job OpportunityGeorge Higginson, Senior Associate at AL Solutions, is partnering with a commercial biopharmaceutical company to find an experienced Principal Biostatistician. The ideal candidate will have a strong background in biostatistics, with expertise in statistical analysis, data interpretation, and clinical trial...
-
Senior Research Investigator
4 weeks ago
Wilmington, Delaware, United States Incyte Full timeJob SummaryThe Senior Research Investigator, Biologics Analytical Development, plays a pivotal role in driving the development of analytical methods to support product release and characterization. This position requires a strong scientific foundation, extensive experience in biologics development, and a deep understanding of ICH guidance.Key...
-
Senior Biostatistician
2 weeks ago
Wilmington, Delaware, United States Al Solutions Full timePrincipal BiostatisticianGeorge Higginson is currently partnering with a commercial biopharmaceutical company to find an experienced Principal Biostatistician. The company is working heavily across the Oncology, Inflammation, and Autoimmunity space.Main Responsibilities:Collaborate with multidisciplinary project teams to establish project timelines and...
-
Financial Crimes Investigator
2 weeks ago
Wilmington, Delaware, United States City National Bank Full timeJob SummaryWe are seeking a highly skilled Financial Crimes Investigator to join our team at City National Bank. As a key member of our compliance team, you will be responsible for analyzing client transactions to ensure compliance with regulatory requirements.Key ResponsibilitiesPerform in-depth analysis of client transactions to identify potential money...
-
Financial Crimes Investigator
2 weeks ago
Wilmington, Delaware, United States City National Bank Full timeFinancial Crimes InvestigatorAt City National Bank, we're committed to preventing financial crimes and ensuring the integrity of our clients' transactions. As a Financial Crimes Investigator, you'll play a critical role in our efforts to detect and prevent money laundering, terrorist financing, and other illicit activities.Key Responsibilities:Conduct...
-
DCVPA Principal
2 months ago
Wilmington, Delaware, United States University of North Carolina Wilmington Full timeAbout the RoleThe DCVPA Principal serves as the leader of the school, responsible for developing and implementing policies, programs, curriculum activities, and budgets that promote the educational development of each student and the professional development of each staff member.Key ResponsibilitiesChief Administrator: Oversee building management, budget,...
-
Principal Robotics Engineer
2 weeks ago
Wilmington, Delaware, United States Vimerse InfoTech Inc Full timeJob Title: Principal Robotics EngineerWe are seeking a highly skilled Principal Robotics Engineer to join our team at Vimerse InfoTech Inc. This is an onsite role, requiring 2-3 days of work per week in Wilmington, MA.Key Responsibilities:Develop control algorithms for mobile robots with 10+ years of experience.Design and implement real-time systems using...
-
Analytical Development Research Scientist
2 months ago
Wilmington, Delaware, United States Incyte Full timeJob SummaryThe Research Scientist, Analytical Development plays a pivotal role in supporting assigned small molecule drug development programs at Incyte, a biopharmaceutical company dedicated to discovering, developing, and commercializing novel medicines for oncology and inflammation and autoimmunity.Key ResponsibilitiesConduct routine and advanced...
-
Wilmington, Delaware, United States The Chemours Company Full timeTransform the Future of Chemistry and the WorldAt Chemours, we're on a mission to create a better world through the power of chemistry. As a key member of our Global Security Team, you'll play a critical role in shaping the future of our industry and the world.Key Responsibilities:Develop and implement internal investigations, global intelligence, and risk...
-
Wilmington, Delaware, United States Incyte Full timeJob SummaryThe Research Scientist, Analytical Development plays a pivotal role in supporting assigned small molecule drug development programs at Incyte, a biopharmaceutical company dedicated to discovering, developing, and commercializing novel medicines for oncology and inflammation and autoimmunity.Key ResponsibilitiesConduct routine and advanced...
-
Wilmington, Delaware, United States The Chemours Company Full timeChemours Global Security Risk ManagerChemours is seeking a highly experienced Global Security Risk Manager to join our Global Security Team. This role will report directly to the Chief Security Officer at our Wilmington, DE location.Key Responsibilities:Develop, implement, and manage internal investigations, global intelligence, and risk programs.Interface...
-
Wilmington, Delaware, United States Incyte Full timeJob SummaryThe Research Scientist, Analytical Development, plays a crucial role in supporting small molecule drug development programs at Incyte. This position involves conducting routine and advanced analytical testing to support pharmaceutical development activities related to drug substance and drug product.Key ResponsibilitiesPerform analyses using...