Director, Protein Engineering and Optimization

1 week ago


Boston, Massachusetts, United States Takeda Pharmaceutical Full time
About the Role

Takeda Pharmaceutical is seeking a highly skilled and experienced Director to lead our Protein/ Antibody Engineering and Optimization team. As a key member of our Global Biologics Department, you will be responsible for driving the development of novel biologics therapeutics through cutting-edge protein and antibody engineering techniques.

Key Responsibilities
  • Lead the design and engineering of biologics therapeutics, including potency/affinity modulation, developability enhancement, bispecific design, and library design.
  • Collaborate with our in-house AI/ML team to integrate computational approaches and de-risk candidates for accelerated identification of viable therapeutics.
  • Develop and implement efficient workflows and modernize the group in all aspects of identifying best practices and internalizing such methods.
  • Drive programs from discovery to IND, integrating early research, progression through candidate nomination and selection.
  • Lead biologics programs, integrating early research, progression through candidate nomination and selection, and ambassador for the biologics department, scientifically inputting to project teams.
  • Manage a team of skilled scientists, empowering them to generate therapeutic biologics, and develop the next generation of organizational and project leaders.
Requirements
  • PhD degree in a scientific discipline with 10+ years of experience, or MS with 16+ years of experience, or BS with 18+ years of experience.
  • 9 years of industry experience required.
  • 9 years of managerial experience required.
  • Outstanding expertise and depth of knowledge within a scientific area, keeping up with the latest scientific advancements.
About Takeda Pharmaceutical

Takeda Pharmaceutical is a patient-focused company that transforms patient care through the development of novel specialty pharmaceuticals and best-in-class patient support programs. We foster an inclusive, collaborative workplace, where our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

We are committed to equitable pay for all employees and strive to be more transparent with our pay practices. We offer a competitive salary range, as well as a comprehensive benefits package, including medical, dental, vision insurance, a 401(k) plan, and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits.



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