Senior Research Associate in Innovative Therapeutics

2 weeks ago


Waltham, Massachusetts, United States TScan Therapeutics Full time
Position Overview

Role Summary:

TScan Therapeutics is at the forefront of biotechnology, aiming to transform therapeutic approaches for patients through the identification of groundbreaking T cells and epitopes. We are in search of a seasoned researcher to fill the role of Senior/Principal Research Associate, contributing to the New Technology and Product Development Team. This position offers a unique opportunity to work at the convergence of biological sciences and engineering, focusing on the advancement of next-generation TCR-T cell products. The ideal candidate will possess substantial experience in T cell immunology, primary and tumor cell culture, cell-based assays, and flow cytometry, thriving in a dynamic and collaborative startup environment.

Key Responsibilities:

  • Contribute to the development of innovative TCR-T cell products.
  • Engage in research aimed at enhancing the TCR-T cell engineering process.
  • Learn, execute, analyze, and present findings from functional assays involving TCR-engineered T cell products (including T cell engineering, flow cytometry, cytotoxicity assays, and cytokine secretion).
  • Maintain cell lines and manage inventory effectively.
  • Document experimental data meticulously in an electronic lab notebook.
  • Present findings in both group and company meetings.

Qualifications:

  • B.S. with 3-5+ years or M.S. with 0-2+ years of experience in biology, immunology, pharmacology, or a related discipline.
  • Preferred proficiency in tissue culture and multi-color flow cytometry, with experience in ELISA and cytotoxicity assays being advantageous.
  • Familiarity with T cell immunology, as well as an understanding of cancer biology and molecular biology, is a plus.
  • Strong communication skills (both written and verbal) and the ability to collaborate in a matrixed environment.
  • A genuine enthusiasm for learning new concepts and techniques, actively participating in journal clubs, and adapting to a fast-paced work environment.

About TScan Therapeutics:

Founded in 2018 by a dedicated group of scientists led by Dr. Stephen Elledge (Harvard Medical School/HHMI), TScan Therapeutics is pioneering the discovery and development of novel TCR-engineered T cell therapies for cancer treatment. Our innovative discovery platform is built on a revolutionary technology that facilitates the rapid and comprehensive identification of peptide antigen targets for T cell receptors. This capability significantly enhances our understanding of the specific antigens involved in critical disease processes, including tumor recognition by the immune system, self-reactivity in autoimmune diseases, and acquired immunity in infectious diseases. TScan is leveraging this platform in oncology to identify new TCR/target pairs and expedite the clinical development of novel TCRs.

Are you ready to make a difference?

At TScan, our talented and compassionate team is what makes our organization a remarkable place to work. Our state-of-the-art facilities, encompassing approximately 40,000 square feet of premium lab and office space, foster an environment that encourages innovation, collaboration, and professionalism. We are driven, passionate, and team-oriented, making TScan a unique workplace.



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