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Senior Research Associate in Innovative Therapeutics
2 months ago
Role Summary:
TScan Therapeutics is at the forefront of clinical biotechnology, aiming to transform therapeutic approaches for patients through the identification of novel T cells and epitopes. We are seeking a skilled researcher to take on the role of Senior/Principal Research Associate, contributing to the New Technology and Product Development Team. This position offers a unique opportunity to work at the convergence of biological sciences and engineering, focusing on the advancement of next-generation TCR-T cell products. The ideal candidate will possess substantial experience in T cell immunology, primary and tumor cell culture, cell-based assays, and flow cytometry, thriving in a dynamic and collaborative startup environment.
Key Responsibilities:
- Contribute to the development of next-generation TCR-T cell products.
- Engage in research aimed at enhancing the TCR-T cell engineering process.
- Conduct, analyze, and present results from functional assays involving TCR-engineered T cell products (including T cell engineering, flow cytometry, cytotoxicity assays, and cytokine secretion).
- Maintain cell lines and manage inventory effectively.
- Document experimental findings in an electronic lab notebook.
- Present findings in team and organizational meetings.
Qualifications:
- Bachelor's degree with 3-5+ years or Master's degree with 0-2+ years of experience in biology, immunology, pharmacology, or a related discipline.
- Preferred proficiency in tissue culture and multi-color flow cytometry, with experience in ELISA and cytotoxicity assays being advantageous.
- Background in T cell immunology, along with an understanding of cancer biology and molecular biology, is a plus.
- Strong communication skills (both written and verbal) and the ability to work effectively in a matrixed environment.
- A proactive attitude and eagerness to learn new concepts and techniques, including participation in journal clubs and adapting to a fast-paced work setting.
About TScan Therapeutics:
Founded in 2018 by a dedicated group of scientists led by Dr. Stephen Elledge, TScan Therapeutics is pioneering the discovery and development of novel TCR-engineered T cell therapies for cancer treatment. Our innovative discovery platform leverages groundbreaking technology to rapidly and comprehensively identify peptide antigen targets of T cell receptors. This capability significantly enhances our understanding of the specific antigens involved in critical disease processes, including tumor recognition by the immune system, self-reactivity in autoimmune conditions, and acquired immunity in infectious diseases. TScan is utilizing this platform in oncology to identify new TCR/target pairs and expedite the clinical development of novel TCRs.
Are you ready to be part of a transformative journey?
Our team at TScan is composed of talented, compassionate, and intelligent individuals, making it an exceptional workplace. Our modern facilities, designed to foster innovation and collaboration, provide an environment that encourages professionalism and teamwork. We are passionate, driven, and flexible, embodying a culture that values both individual contributions and collective success.
