Principal Investigator

1 week ago


Kansas City, Missouri, United States KCAS Bio Full time
About the Role

We are seeking a highly skilled and experienced Senior Research Scientist to join our team at KCAS Bio. As a key member of our BioPharma LBA/Biomarker Services lab team, you will be responsible for leading and executing bioanalytical validations and biostudies, providing scientific expertise in study design, conduct, and interpretation, and mentoring research staff in areas such as protocol interpretation, method development, and refinement.

Key Responsibilities
  • Function independently as a technical expert in the direction and execution of bioanalytical validations and biostudies
  • Provide oversight of the laboratory and mentor research staff in areas such as protocol interpretation, method development, and refinement, study related problem resolution, and technique validation
  • Independently review, interpret, analyze, evaluate, and discuss study results with research staff and sponsors
  • Prepare high-quality final reports appropriate for the study, including integration of supporting subcontractor's reports into final reports as required
  • Supervise research and scientific staff within the function
  • Direct activities of assigned group(s), to ensure effective performance of function
  • Review protocols, reports, and scientific documents of direct reports as required
  • Provide scientific and technical leadership within designated business unit to resolve analytical challenges promptly and evaluate new technologies for potential integration into existing portfolio of services
Requirements
  • Bachelor's, Master's, or PhD in a related field
  • At least 10 years of relevant experience within contract research, academic, or pharmaceutical industry, including expertise in the core competencies of validation and bioanalysis of study samples
  • Full understanding of GLPs, and departmental/company SOPs
  • Experience designing, planning, and executing bioanalytical assays (ADA, PK, Biomarker, and Nab), method development and validation
  • Proficient in using common immunoassay platforms (ELISA, MSD, Luminex, etc.)
  • Experience designing complex experiments & evaluating outcome vs. regulatory guidelines, white papers, and current industry practices
  • Experience troubleshooting problems and actively participating in the life cycle management of assays
  • Ability to manage multiple moderate to complex projects, prioritizes work, and meets deadlines
  • Capable of anticipating and recognizing potential problems within programs and effectively communicating alternatives to clients in a meaningful fashion
  • Must have a proven record of delivering quality service to customers on time and on budget
  • Expert knowledge of applicable lab techniques
  • Familiarity with current industry trends and expectations
  • Demonstrated proficiency with validation, experimental design, troubleshooting, and method development as required by department
About KCAS Bio

We are a fast-growing contract research organization (CRO) headquartered in Kansas City, pioneering the latest drug development in both human and animal health fields. Demand for our expertise is growing and so is our need for great people to work in nimble, empowered teams committed to one another's growth.

We advance both great science AND great people. KCAS Bio is proud to be an Equal Opportunity Employer. We provide equal employment opportunities without regard to race, color, religion, national origin, ancestry, marital status, veteran status, age, disability, pregnancy, genetic information, sex, sexual orientation, gender identity, or any other legally protected category.



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