Senior Computational Biologist

1 week ago


South San Francisco, California, United States R&D Partners Full time
Job Description

R&D Partners is seeking a highly skilled Computational Scientist to join our Computational Biology group. As a key member of our team, you will play a crucial role in supporting novel insight generation and driving our pipeline and clinical research goals.

Key Responsibilities
  • Collaborate with Scientists in Oncology to analyze large-scale single-cell and bulk RNA, TCR, ADT, and ATAC-seq datasets to address scientific hypotheses and deliver novel insights.
  • Develop Analytical Approaches to integrate and interpret these data, delivering insights into disease biology and mechanisms of action.
  • Coordinate Data Processing and standardization of newly incoming datasets to make them analysis-ready.
  • Document Code and Analysis processes, including standardization of analytical workflows.
  • Present Findings to the group and Oncology collaborators.
Qualifications
  • PhD or Master's with significant experience in Computational Biology, Bioinformatics.
  • Extensive experience in large-scale single-cell data analysis (RNA, TCR, ADT, ATAC), including gold-standard methods and novel, advanced analytical techniques such as:
  • Multimodal Data Integration methods
  • Cell Phenotyping Approaches, including topic modeling
  • Clonotype Analysis
  • TCR-Sequence Analysis
  • Expertise in (immuno)-oncology, innate immunity, and/or T cell biology.
  • Proficiency in R, Python, and shell scripting.
  • Experience working with Git and high-performance computing.
  • High Self-Motivation and commitment to delivering high-quality results.
  • Ability to produce high-quality analysis results with minimal supervision, including meeting key deadlines and making sensible independent decisions.
  • Excellent Communication Skills and experience working as part of a team.
  • Curiosity and desire to learn more about computational biology and immuno-oncology biology.
Benefits
  • Comprehensive benefits package including medical insurance, dental and vision insurance, 401k plan, employee assistance program, long-term disability, weekly payroll, expense reimbursement, and online timecard approval.


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