Computational Biologist
2 months ago
Software Guidance & Assistance, Inc., (SGA), is seeking a highly skilled Computational Scientist - Cancer Immunogenomics for a contract assignment with one of our premier Pharmaceutical services clients in the industry.
Key Responsibilities- Collaborate with scientists in Oncology to analyze large-scale single-cell and bulk RNA, TCR, ADT, and ATAC-seq datasets to address scientific hypotheses and deliver novel insights.
- Develop analytical approaches to integrate and interpret these data, delivering insights into disease biology and mechanisms of action to propel our pipeline and clinical research goals.
- Coordinate the processing and standardization of newly incoming datasets to make them analysis-ready.
- Document code, analysis processes, and findings, including standardization of analytical workflows.
- Present findings to the Cancer Immunogenomics group and Oncology collaborators.
- Extensive experience in large-scale single-cell data analysis (RNA, TCR, ADT, ATAC), including gold-standard methods and novel, advanced analytical techniques such as:
- Multimodal data integration methods
- Cell phenotyping approaches, including topic modeling
- Clonotype analysis
- TCR-sequence analysis
- Expertise in (immuno)-oncology, innate immunity, and/or T cell biology.
- PhD (or Master's with significant experience) in Computational Biology, Bioinformatics, or a related field.
- Proficiency in R, Python, and shell scripting.
- Experience working with Git and high-performance computing.
- High self-motivation and commitment to delivering high-quality results.
- Ability to produce high-quality analysis results with minimal supervision, including meeting key deadlines and making sensible independent decisions.
- Excellent communication skills and experience working as part of a team.
- Curiosity and desire to learn more about computational biology and immuno-oncology biology.
SGA is a leading provider of IT resource solutions, with a strong presence in the Pharmaceutical services industry. Our company has a proven track record of delivering high-quality results and meeting the needs of our clients. We are committed to excellence and innovation, and we are seeking a talented Computational Scientist to join our team.
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