Senior Scientist/Associate Director, Clinical Biomarkers
2 days ago
The Senior Scientist/Associate Director of Clinical Biomarkers will play a pivotal role in advancing biomarker strategies to support the clinical development of Nurix's innovative therapies targeting protein homeostasis.
This position requires a leader who can collaborate across research, clinical development, and external partnerships to drive the biomarker strategy for early phase clinical trials.
The successful candidate will leverage deep expertise in cell and tumor biology, molecular biology, inflammation, and immuno-oncology to design and interpret both preclinical and clinical biomarker studies.
Key Responsibilities:
- Oversee biomarker assay development, including assay qualification and execution on diverse platforms, to support pharmacodynamic and predictive biomarker analysis in clinical trials.
- Lead the evaluation and implementation of novel biomarker assays in both nonclinical models and patient-derived samples, ensuring alignment with clinical trial objectives.
- Collaborate closely with multidisciplinary teams, including research scientists, clinical development, external collaborators, and contract research organizations (CROs), to ensure seamless integration of biomarker data into clinical development plans.
- Provide scientific and strategic input into clinical trial designs, ensuring biomarker data are effectively utilized to guide therapeutic decisions and optimize patient outcomes.
- Mentor and manage junior scientists, fostering a collaborative and innovative research environment.
Requirements:
- Ph.D. or equivalent in a relevant scientific area, with 4+ years of experience in a relevant scientific area within the pharmaceutical or biotech industry.
- Proven expertise in the development, qualification, and implementation of clinical biomarker assays, particularly in the areas of inflammation, immuno-oncology, cancer biology, or related therapeutic areas.
- Extensive technical experience across diverse platforms, including flow cytometry, molecular biology, proteomics, and tissue-based assays.
- Strong organizational and project management skills, with the ability to lead multiple projects simultaneously in a fast-paced environment.
- Excellent communication and interpersonal skills, with the ability to present complex biomarker data to both scientific and clinical audiences, as well as external stakeholders.
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