Senior Scientist, Biomarker Assay Development Specialist

3 weeks ago

San Diego, California, United States Neurocrine Biosciences Full time

About the Role:

We are seeking a highly skilled Senior Scientist to join our team at Neurocrine Biosciences. As a Senior Scientist, you will be responsible for developing and validating biomarker assays to help confirm drug target engagement, understand mechanisms of action and patient response.

Your Key Responsibilities:

  • Design, develop, and perform robust "fit-for-purpose" clinical biomarker assays
  • Identify and evaluate new technologies to support evolving translational biomarker strategies
  • Collaborate closely with internal pre-clinical and clinical colleagues as well as external partners to deliver translational biomarker strategies for drug development candidates
  • Provide technical guidance on assay validation and serve as a subject matter expert in immunoassay-based assay development and validation
  • Collaborate with external academic and industry experts to expand Neurocrine's knowledge base in biofluid biomarkers
  • Generate and work with complex data sets, with a strong understanding of advanced data analysis and statistical tests
  • Maintain and update SOPs and write data summaries for experiments conducted
  • Review, comprehend, and comply with all SOPs, and safety and quality assurance standards at all times
  • Provide training and/or supervision to junior staff, as needed

Requirements:

  • BS/BA degree and 5+ years of relevant experience, OR
  • MS/MA degree and 3+ years of relevant experience OR
  • PhD or equivalent and some relevant experience; may include postdoc experience
  • Track record of successful implementation of immunoassays, proteomics, and cell-based assays (e.g., flow cytometry) for biomarker discovery using pre-clinical or clinical samples
  • Extensive experience working with tissue samples and/or biofluids
  • Experience with some of these techniques: ELISA, IP, western blotting, flow cytometry, high content imaging, HTRF
  • Experience with managing contract research organizations
  • Hands-on experience with the pros and cons of different biomarker assay platforms (eg. Luminex, MesoScale Discovery and/or SIMOA) is preferred
  • Exosome purification in humans and non-clinical species is a plus
  • Experience working with human biospecimens is a plus

What We Offer:

Neurocrine Biosciences is an EEO/AA/Disability/Vets employer. We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.

The annual base salary we reasonably expect to pay is $106,400.00-$154,325.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity-based long-term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

  • Senior Scientist/Associate Director, Clinical Biomarkers

    4 weeks ago

    San Francisco, California, United States Nurix Full time

    Job SummaryThe Senior Scientist/Associate Director of Clinical Biomarkers will play a pivotal role in advancing biomarker strategies to support the clinical development of Nurix's innovative therapies targeting protein homeostasis.This position requires a leader who can collaborate across research, clinical development, and external partnerships to drive the...

  • Senior Research Scientist, Assay Development Expert

    3 weeks ago

    San Diego, California, United States BioPhase Solutions Full time

    Job OverviewThe Senior Scientist, Assay Development Expert will play a key role in the development of innovative diagnostic platforms at BioPhase Solutions. This hands-on position requires a detail-oriented and innovative individual with a solid understanding of immunochemistry and protein biochemistry.Key ResponsibilitiesAntibody Conjugations and...

  • Senior Biomarker Scientist

    4 weeks ago

    San Francisco, California, United States Daiichi Sankyo, Inc. Full time

    Unlock the Power of Biomarker Innovation Daiichi Sankyo Group is a global leader in pharmaceutical therapies, dedicated to improving standards of care and addressing unmet medical needs worldwide. With a rich legacy of innovation and a robust pipeline of promising new medicines, we're committed to advancing the field of biomarker research. Job Summary: This...

  • Senior Scientist, Translational Sciences Study Lead

    4 weeks ago

    San Diego, California, United States Disability Solutions Full time

    Senior Scientist, Translational Sciences Study LeadJohnson & Johnson is seeking a Senior Scientist to join our Translational Sciences team. As a key member of our Immunology Translational Sciences department, you will contribute to the design and conduct of translational science research to support our immunology portfolio.Key Responsibilities:Contribute to...

  • Senior Scientist, Assay Development Specialist

    4 weeks ago

    San Bernardino, California, United States Allen Spolden Full time

    Job Title: Principal Scientist, Assay DevelopmentA highly skilled and experienced Principal Scientist is sought to join our team at Allen Spolden, where you will play a key role in developing innovative NGS-based assays from concept to commercialization. As a senior member of our team, you will be responsible for directing, mentoring, and contributing to...

  • Research Scientist

    3 weeks ago

    South San Francisco, California, United States Innova solutions Full time

    Job SummaryInnova Solutions is seeking an Associate Research Scientist to join our team. As an Associate Research Scientist, you will assist with the development and implementation of histopathology assays, including single and multiplex immunohistochemistry (IHC) assays, in situ hybridization (ISH), and use a variety of imaging modalities.Key...

  • Custom Assay Development Specialist

    3 weeks ago

    San Diego, California, United States Revvity Full time

    Company OverviewRevvity is a pioneering developer and provider of end-to-end solutions designed to empower scientists, researchers, and clinicians to tackle the world's most pressing health challenges. We combine the enthusiasm of an industry disruptor with the experience of a longtime leader, fostering a diverse team of over 11,000 colleagues from around...

  • Associate Director/Senior Principal Scientist of Translational Medicine

    4 weeks ago

    San Diego, California, United States Bristol-Myers Squibb Full time

    Transforming Patients' Lives through ScienceBristol Myers Squibb is a leading pharmaceutical company dedicated to transforming patients' lives through science. We are seeking a highly skilled Associate Director/Senior Principal Scientist of Translational Medicine to join our team.Key Responsibilities:Design and implement program-specific late development...

  • Translational Research Scientist

    4 weeks ago

    San Diego, California, United States Tr1X Full time

    Job Title: Scientist I, Translational SciencesTr1X is seeking an experienced translational researcher to lead the execution of biomarker strategies and correlative studies for early clinical development.About the RoleThis role involves working with human blood and tissues. The ideal candidate will have proven expertise in bioanalytical strategies for...

  • Scientist Intern

    4 weeks ago

    San Diego, California, United States Bristol Myers Squibb Full time

    **Transforming Lives through Science**Bristol Myers Squibb is a leading pharmaceutical company that is dedicated to transforming patients' lives through science. We are seeking a highly motivated and talented individual to join our Translational Research group as a Scientist Intern.As a Scientist Intern, you will have the opportunity to work on cutting-edge...

  • Senior Research Scientist

    3 weeks ago

    South San Francisco, California, United States Genentech Full time

    Key Responsibilities:As a member of our dynamic team at Genentech, you will be responsible for:Discovering and evaluating candidate targets or biomarkers to drive innovation in translational medicine.Developing and implementing biomarker assays in preclinical models and clinical trials to advance our understanding of respiratory diseases.Evaluating new...

  • Senior Vice President, Translational Biology and Immunology

    4 weeks ago

    San Francisco, California, United States Vir Biotechnology, Inc. Full time

    About the RoleWe are seeking an experienced Senior Vice President, Translational Biology and Immunology, to join our team at Vir Biotechnology, Inc. This role will oversee our Translational Biology department, leading a team of translational and clinical biomarker scientists in developing and executing biomarker-driven clinical trials. The ideal candidate...

  • Scientist I

    4 weeks ago

    South San Francisco, California, United States Orion Engineering Services Full time

    Job Title: Scientist I - Flow Cytometric Assays SpecialistJob Summary:Orion Engineering Services is seeking a highly motivated Scientist to work with our global pharmaceutical client in South San Francisco, CA. This Scientist will support the development and implementation of single cell-based flow cytometric (FCM) assays that enable development of novel...

  • Senior Scientist, Product Transfer Specialist

    4 weeks ago

    San Diego, California, United States Ortho Clinical Diagnostics Full time

    The OpportunityAt Ortho Clinical Diagnostics, we are seeking a highly skilled Senior Scientist to join our team as a Product Transfer and Validation Specialist. This role will be responsible for supporting the transfer and validation of molecular diagnostic assays, assay formulations, QC methods, and testing processes into manufacturing.The RoleThis position...

  • Research Scientist

    4 weeks ago

    San Diego, California, United States Net2Source Inc. Full time

    Job Title: Research ScientistNet2Source Inc. is seeking a highly skilled Research Scientist to join our team in San Diego, CA.Job Summary:We are looking for a talented Research Scientist with expertise in cell biology, immunology, and molecular biology to support our oncology-based drug discovery efforts. The successful candidate will design and conduct...

  • Senior Analytical Development Scientist

    4 weeks ago

    San Diego, California, United States Meet Full time

    Job Opportunity: Principal Scientist, Analytical DevelopmentMeet is partnering with a clinical stage biotech to fill a key role in their San Diego-based team. The ideal candidate will have expertise in late-stage analytical method development, qualification, validation, and life-cycle management.Key Responsibilities:Develop and implement analytical methods...

  • Associate Scientist

    2 weeks ago

    South San Francisco, California, United States Innova Solutions Full time

    About the Role:Innova Solutions is seeking an Associate Scientist to join our team. As an Associate Scientist, you will be responsible for assisting with the development and implementation of histopathology assays, including single and multiplex immunohistochemistry (IHC) assays, in situ hybridization (ISH), and other advanced microscopy...

  • Research Scientist III

    4 weeks ago

    San Mateo, California, United States Net2source Full time

    Job Title: Associate Scientist - Biology Immuno-oncologyWe are seeking a highly motivated and talented Associate Scientist to join our Immuno-oncology group at Net2source. Our collaborative and interdisciplinary research team utilizes state-of-the-art technologies and innovative methodologies to advance medicines into the clinic.The successful candidate will...

  • Research Scientist

    4 weeks ago

    San Diego, California, United States Revvity Full time

    Job SummaryThis position is responsible for supporting immunoassay product development and manufacturing in the Biomarker Immunoassay group. The successful candidate will be involved in all aspects of the product development process, including designing, initiating, testing, troubleshooting, and testing materials manufacturing. They will work with an...

  • Senior Scientist

    4 weeks ago

    San Jose, California, United States Takara Bio Full time

    Job Summary: We are seeking a highly skilled and collaborative R&D Scientist with expertise in NGS to drive innovation within Takara's portfolio. The scientist will lead projects with guidance from senior scientific staff, taking responsibility for designing, executing, and analyzing experiments to develop novel NGS technologies and products.Key...