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Research Scientist II

2 months ago


South San Francisco, California, United States BEPC Inc. - Business Excellence Professional Consulting Full time
Job Title: Research Scientist II

BEPC Inc. - Business Excellence Professional Consulting is seeking a highly motivated and experienced Research Scientist II to join our Antibody Engineering Department.

Job Summary:

We are looking for a talented scientist with strong molecular biology skills and experience in the design and assembly of antibody encoding plasmids for expression from mammalian cells.

The Opportunity:

  • Work with our team of scientists to develop and engineer therapeutic antibody candidates.
  • Apply molecular biology skills to drive the rapid assembly of antibody encoding plasmids for expression from mammalian cells.
  • Collaborate with automation engineers to build and develop workflows for high throughput, automated processes for DNA plasmid assembly and clonal mAb selection.
  • Interact with informatic engineers to develop processes that support automated antibody development workflows including antibody (DNA and protein sequence) registration, tracking, archiving, and inventory.

Requirements:

  • B.S. or M.S. degree in molecular biology or related science and 4+ years of applying molecular biology skills, preferably in an antibody research or industrial setting.
  • Experience and expertise in performing polymerase chain reactions (PCR), general DNA plasmid construct assembly, steps necessary for antibody clone isolation including bacterial transformation, bacterial colony picking, bacterial clone culturing, plasmid purification at the mini to maxi scale, and analyzing DNA sequences.
  • Experience in working with tools for antibody DNA sequence analysis, sequence confirmation, and sequence alignment is essential.
  • Basic molecular biology skills in DNA ligation, DNA mutagenesis, oligonucleotide design, and endonuclease restriction digestion analysis are also required. Experience with surface plasmon resonance (SPR), performing binding ELISAs and graphing is preferred.
  • Must have excellent record keeping skills, strong communication skills, and be experienced in data management using Excel or Google Drive.

What We Offer:

  • 1 year contract with possible extensions
  • Benefits include Medical, Dental, Vision, and Life Insurance
  • Pay Rate: $45.00-$48.61