Scientist Antibody Discovery Specialist

13 hours ago


South San Francisco, California, United States Global Channel Management, Inc Full time
Scientist Antibody Discovery Job Description

We are seeking a highly motivated and experienced Scientist Antibody Discovery to join our team at Global Channel Management, Inc.

Key Responsibilities:

  • Design and execute antibody discovery campaigns for therapeutic and reagent antibodies using phage display
  • Generate antibody fragment libraries for antibody discovery and engineering, perform HT binding screens (ELISA and multi-plex flow cytometry) and sequence analysis to generate hits
  • Rank-order clones by affinity, in vitro potency, and early developability assessment
  • Execute sequence optimization of lead antibodies to improve developability and binding affinity

Requirements:

  • PhD in Biochemistry, Biomedical/Chemical Engineering, Immunology, or related field with minimum of 2 years of post-graduate experience (preferably in industry)
  • Strong background in molecular biology, antibody and protein expression, and biophysical characterization of recombinant antibodies and proteins
  • Demonstrated experience in working collaboratively across various scientific disciplines and other parts of the organization to meet end goals
  • Highly motivated individual with exceptionally good organizational skills, and attention to details

Preferred Qualifications:

  • Experience in single domain antibodies, multi-specific antibody engineering, Fc engineering, antibody drug conjugates, naïve phage or yeast display library design
  • Experience in NGS analysis for antibody discovery and engineering
  • Significant contributions to successful biologics drug discovery programs in biotech/biopharma industry

What We Offer:

At Global Channel Management, Inc, we offer a dynamic and collaborative work environment, competitive compensation and benefits package, and opportunities for professional growth and development.



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