Scientist Antibody Discovery Specialist
13 hours ago
We are seeking a highly motivated and experienced Scientist Antibody Discovery to join our team at Global Channel Management, Inc.
Key Responsibilities:
- Design and execute antibody discovery campaigns for therapeutic and reagent antibodies using phage display
- Generate antibody fragment libraries for antibody discovery and engineering, perform HT binding screens (ELISA and multi-plex flow cytometry) and sequence analysis to generate hits
- Rank-order clones by affinity, in vitro potency, and early developability assessment
- Execute sequence optimization of lead antibodies to improve developability and binding affinity
Requirements:
- PhD in Biochemistry, Biomedical/Chemical Engineering, Immunology, or related field with minimum of 2 years of post-graduate experience (preferably in industry)
- Strong background in molecular biology, antibody and protein expression, and biophysical characterization of recombinant antibodies and proteins
- Demonstrated experience in working collaboratively across various scientific disciplines and other parts of the organization to meet end goals
- Highly motivated individual with exceptionally good organizational skills, and attention to details
Preferred Qualifications:
- Experience in single domain antibodies, multi-specific antibody engineering, Fc engineering, antibody drug conjugates, naïve phage or yeast display library design
- Experience in NGS analysis for antibody discovery and engineering
- Significant contributions to successful biologics drug discovery programs in biotech/biopharma industry
What We Offer:
At Global Channel Management, Inc, we offer a dynamic and collaborative work environment, competitive compensation and benefits package, and opportunities for professional growth and development.
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