Research Associate Scientist Investigative Toxicology
3 days ago
Job Summary:
Takeda Pharmaceutical is seeking a highly motivated Research Associate Scientist to join our Global Investigative Toxicology team. As a key member of our team, you will contribute to the detection and de-risking of toxicity in our portfolio to help make medicines safer and more effective.
Key Responsibilities:
- Design and implement early safety assessment screening strategies to enable the progression of optimized therapeutic candidates.
- Conduct cell-based in vitro assays to characterize immune-mediated toxicities for medicines in discovery & development.
- Develop novel in vitro model systems to assess safety risks associated with new therapeutic designs.
- Maintain cultures of immortalized tumor cell lines, primary cell types of various origin, and primary immune cells.
- Perform fit-for-purpose ex vivo analyses to assess phenotypic and functional correlates of toxicity.
- Prepare experimental protocols, analyze experimental data, and present study results in team and department meetings.
- Contribute ideas to drive innovation within investigative toxicology and with key collaborators.
Requirements:
- MS. with 3+ years or BS with 5+ years of experience in immunology, biology, biochemistry, pharmacology, or a related discipline.
- Expert with standard aseptic cell culture technique, including experience culturing various tumor cell lines and primary cells.
- Broad experience with cell-based functional assays, including cytotoxicity, cytokine release, and proliferation assays.
- Basic experience with molecular biology techniques including RNA/DNA extraction, qPCR, western blot.
- Experience working in a matrixed team environment at a pharmaceutical company and/or CRO.
- Broad scientific knowledge in immunology and pharmacology.
- Self-motivated with strong time management and organizational skills.
- Ability to balance multiple projects and flexible with changing priorities.
- Highly collaborative with demonstrated ability to work in a matrixed team environment.
- Excellent oral and written communication skills.
What We Offer:
- Competitive salary range: $96,000 - $151,800.
- Short-term and long-term incentives.
- Medical, dental, vision insurance.
- 401(k) plan and company match.
- Short-term and long-term disability coverage.
- Basic life insurance.
- Tuition reimbursement program.
- Paid volunteer time off.
- Company holidays.
- Well-being benefits.
Equal Employment Opportunity:
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
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