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Senior Research Scientist

1 month ago

South San Francisco, California, United States LanceSoft Full time
Job Title: Scientist I

Job Summary:
We are seeking a highly motivated and experienced Scientist I to join our team at LanceSoft. The successful candidate will have a strong background in bioanalytical chemistry and in vitro ADME assays, with a proven track record of developing and implementing LC-MS/MS methods for the quantitative analysis of small molecules.

Key Responsibilities:
  • Conduct in vitro ADME assays, including stability assays, metabolic stability assays, and Cytochrome P450 inhibition and induction assays
  • Develop and maintain cell cultures, including primary and derived cell lines
  • Perform metabolite profiling, identification, and quantification
  • Develop and implement bioanalytical LC-MS/MS methods for the quantitative analysis of small molecules
  • Quantitate drug concentrations in various biological matrices
  • Integrate and analyze data, with a focus on supporting discovery project teams

Requirements:

  • MS degree with 1-3+ years of experience in DMPK and/or bioanalytical chemistry or related field
  • Hands-on knowledge of in vitro DMPK assays
  • Experience with cell culture and LC-MS/MS methods
  • Strong organizational, record-keeping, presentation, and communication skills
  • Ability to work independently with minimal supervision and multitask

What We Offer:

We offer a dynamic and collaborative work environment, with opportunities for professional growth and development. If you are a motivated and experienced scientist looking for a new challenge, please submit your application.