Lead Solid State Chemist

2 weeks ago


North Chicago Illinois, United States AbbVie Full time
Job Overview

AbbVie is in search of a dedicated and innovative scientist to join our MPDD organization as a Lead Solid State Chemist. This role is ideal for individuals with a solid background in solid form development, material sciences, and molecular modeling.

Key Responsibilities

The Molecular Profiling and Drug Delivery (MPDD) team within the Small Molecule CMC organization is responsible for a diverse array of deliverables throughout various phases of drug discovery and development.

As a member of this team, you will:

  • Utilize advanced automation and computational tools during lead optimization and candidate selection.
  • Collaborate with cross-functional teams to enhance the probability of success for candidates moving into development.
  • Advise on clinical formulation strategies based on solid-state chemistry expertise.
Development Phases

Throughout the development process, you will engage in:

  • Identifying the optimal solid form of the active pharmaceutical ingredient (API).
  • Establishing structure-property-performance correlations to facilitate robust commercial processes.
  • Aligning control strategies across both drug substance and product.
Collaboration and Innovation

As a Solid State Chemist at AbbVie, you will work closely with various teams to:

  • Support projects from Lead Optimization to Process Validation.
  • Identify the best molecules for development and create scalable API isolation processes for early clinical studies.
  • Work with engineers and formulation scientists to deliver commercial API isolation processes with optimized physical properties.
Regulatory Compliance

In the later stages of development, you will ensure alignment of control strategies across API and drug product, collaborating with relevant teams to facilitate successful regulatory submissions.

Technical Expertise

To develop and implement effective solutions, you will employ a diverse range of experimental and analytical techniques, alongside automation and modeling tools.

This position offers a unique opportunity to lead within dynamic, multidisciplinary project teams, applying your expertise in a function with diverse responsibilities across development phases.


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