Protein Therapeutics Researcher

2 weeks ago


Boulder, Colorado, United States Mosaic Biosciences Full time
Position Overview

Senior Scientist in Protein Sciences

Mosaic Biosciences is on the lookout for a dedicated Senior Scientist to enhance our Protein Sciences division. This role involves collaboration within a multidisciplinary team focused on advancing protein therapeutics from initial discovery through to preclinical stages.

Key Responsibilities:
  • Develop, execute, and refine protocols for the recombinant expression of proteins across various cell systems including bacterial, mammalian, yeast, and insect cells.
  • Diagnose and enhance complex purification processes to isolate proteins effectively.
  • Utilize diverse bioconjugation methodologies for the labeling of proteins with small molecules, oligonucleotides, and polymers.
  • Contribute actively to project teams, fostering a collaborative environment.
  • Support routine maintenance of laboratory instruments.
  • Keep a meticulous and precise laboratory notebook documenting all research activities.
Qualifications:
  • Ph.D. or equivalent in Chemistry, Biochemistry, Molecular Biology, Chemical Biology, or a related discipline, accompanied by relevant industry experience.
  • Proven expertise in protein engineering and the design of constructs for recombinant protein expression.
  • Experience with the recombinant expression of proteins in various cell types.
  • Familiarity with aseptic cell culture techniques and the transfection of cell lines, including stable cell line generation.
  • Proficient in protein purification utilizing various techniques, including automated chromatography systems and multi-dimensional purification strategies.
  • Knowledge of various bioconjugation techniques.
  • Ability to devise innovative solutions to complex challenges.
  • A track record of scientific publications demonstrating the application of the aforementioned skills.
  • Strong time management and resource allocation skills, with a passion for teamwork. Capable of conducting independent lab research and method development with minimal supervision.
  • Exceptional verbal and written communication skills, with a keen attention to detail.

This is a full-time opportunity with a competitive compensation range and comprehensive benefits, including health and dental insurance, disability and life insurance, a 401k plan with company matching, and performance-based bonuses.

Mosaic Biosciences, Inc. is committed to fostering a diverse and inclusive workplace that values all backgrounds and promotes individuality, driving scientific innovation and providing equal opportunities for all.



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