Postdoctoral Research Scientist Position

5 days ago


New York, New York, United States Columbia University Full time
Postdoctoral Research Scientist Opportunity

The Division of Surgical Science of Surgery at Columbia University Vagelos College of Physicians and Surgeons is seeking a highly motivated Postdoctoral Research Scientist to join our team. Under the supervision of the Principal Investigator, the individual will train in developing and participating in a research project that focuses on cellular and molecular mechanisms underlying neuronal degeneration relevant to basic and translational studies in novel transgenic mouse models of aging and Alzheimer's disease.

Responsibilities:
  • Conduct laboratory research in the area of neurodegeneration and mitochondrial function.
  • Perform cell and neuronal culture, transfection of gene expression in primary and continuous cell lines, viral transfections in vitro and in vivo, and mouse brain injection.
  • Immunostaining/fluorescence and confocal microscopy imaging and neuropathology in vitro cultured neurons and in vivo brain sections.
  • Immunoblotting, ELISA, and RNA analysis for protein expression and pattern and gene changes, and mouse behavior.
  • Conduct literature searches, manage data, analyze experimental results, and published data. Participate in the development of an extramurally funded research program by assisting PIs with NIH grants.
Requirements:
  • PhD, MD, or MD/PhD
  • Experience in biochemistry and molecular biology
  • Participation in research projects related to mitochondrial function and structure changes
  • Previous experience with immunostaining, neuronal culture, confocal microscopy
  • The ability to assist with writing scientific papers and grant applications


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