Manufacturing Science and Technology Leader

3 days ago

Richmond, Virginia, United States Virginia Jobs Full time
Job Summary

Virginia Commonwealth University's Medicines for All (M4ALL) is a pioneering institute dedicated to revolutionizing global access to life-saving medicines. We achieve this through innovative synthetic process development and advanced technology deployment to reduce costs and waste in small molecule drug substance manufacturing. Our work supports treatments for diseases such as COVID-19, HIV, TB, and malaria.

Key Responsibilities
  • Oversee the implementation of robust and efficient manufacturing processes and the continuous advancement of M4ALL's manufacturing assets and capabilities.
  • Lead efforts to develop, optimize, and scale up manufacturing processes for drug substances and drug products.
  • Design laboratory experiments to support process design, optimization, and technology transfer objectives.
  • Ensure thorough characterization of intermediate and API processes and products.
  • Define scientifically robust, defensible control strategies for API manufacturing and reduce them to practice via unit operation requirements.
  • Manage the transfer of manufacturing processes from development to clinical and commercial production - internally, and to third-party manufacturing operations.
  • Collaborate with process chemists and engineers to develop, and advance robust manufacturing processes - internally, and at third-party manufacturers.
  • Identify and implement advanced technologies and innovative approaches to improve manufacturing processes and capabilities.
Requirements
  • Strong technical background in small molecule drug substance manufacturing.
  • Passion for building and leading high-functioning manufacturing teams.
  • Excellent problem-solving skills.
  • Foster a culture of safe operations, stringent regulatory compliance, and continuous improvement.
  • Strong communication, organizational, and leadership skills.
  • Collaborate with cross-functional teams to ensure alignment and effective communication.

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