Senior Quantitative Scientist

4 days ago


Worcester, Massachusetts, United States AbbVie Full time

Company Overview

AbbVie is a global, research-based biopharmaceutical company dedicated to developing innovative therapies to address the world's most complex and serious diseases. With a portfolio of marketed products in areas including eye care, immunology, oncology, virology, and women's health, AbbVie employs approximately 47,000 people worldwide and markets medicines in more than 175 countries.

Job Description

We are seeking an experienced project representative to provide small molecule project support across all therapeutic areas for molecules in discovery and clinical development. The successful candidate will collaborate with Discovery and Development project teams, clinical pharmacology, and other stakeholders to develop and execute strategies necessary to facilitate the advancement of our pipeline.

Key Responsibilities:

  • Serve as a project representative on multidisciplinary project teams supporting the development of novel small molecules;
  • Develop and drive project strategies for small molecule discovery, preclinical, and clinical development;
  • Effectively communicate project strategies and knowledge to project teams, functional leaders, and other key stakeholders;
  • Demonstrate thorough understanding of ADME sciences and PK/PD aspects necessary to optimize drug candidates;
  • Coordinate and request ADME, PK and PK/PD studies in a timely manner and communicate protocols, timelines, needs and results back to team;
  • Integrate ADME, PK, PK/PD data with discovery biology data and provide thought leadership to project teams;
  • Prepare project sections of regulatory submission documents (IND, IB, NDA);
  • Mentor junior project reps.

Required Skills and Qualifications

The ideal candidate will possess a PhD in Biochemistry, Drug Metabolism, Pharmacokinetics, Pharmaceutical Sciences, or related area with 6+ years of experience in the pharmaceutical or biotechnology industry, or MS with 12+ years, or BS with 14+ years of industry experience. Key skills include expertise in PK analysis and relevant data analysis software such as Phoenix/WinNonlin, ability to quickly adapt in-house visualization tools for data interpretation and presentation, strong understanding of Drug Metabolism, PK, PK/PD modeling, human PK and DDI prediction strategies, and demonstrated scientific leadership.

Salary and Benefits

The estimated salary for this position is $120,000 - $180,000 per year, depending on qualifications and experience. AbbVie offers a comprehensive package of benefits, including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) to eligible employees.



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