Senior Scientist, DMPK Advisory Services

1 day ago


Somerset, New Jersey, United States Catalent Inc Full time
Job Summary

Catalent is seeking a highly skilled Principal Scientist, DMPK Advisory Services to lead and execute pharmacokinetic modeling for the US region and support PK modeling for other regions. The successful candidate will leverage internal scientific community and external collaborations to drive Catalent's brand for drug delivery technologies.

Key Responsibilities
  • Perform in silico modeling to model drug absorption in various animal species to select most appropriate molecules for evaluation as a drug and confirm viability of dosing route.
  • Based on in vitro and in vivo data, perform in silico modeling to estimate rate and extent of absorption of drug molecules from at least 3 human dosing routes.
  • Apply absorption models to evaluate the effect of modified release on rate and extent of absorption to mitigate dose frequency, efficacy, and toxicity limitations.
  • Perform modeling in specific patient populations (e.g. pediatric, geriatric, or special patient populations) upon request.
  • Partner with Business Development in the US region for new and existing business opportunities for assigned projects or technologies.
  • Participate in the creation of Catalent Scientific Advisory strategy.
  • Participate in the creation and execution of Catalent scientific editorial line.
  • Support assigned Product Development efforts in the region.
Requirements
  • Bachelor's Degree in Life Sciences, required.
  • Seven+ years of experience in the pharmaceutical industry and five+ years of PBPK modeling, required.
  • Thorough expertise in Gastro plus and PBPK modeling.
  • Experience in biopharmaceutics and bioavailability enabling technologies, preferred.
  • Experience in multiple market segments (Rx) and unit dosage forms, with strong background in solving poor bioavailability issues and modified release.
  • Up to 15% travel expectations (globally).
  • Individual may be required to sit, stand, walk regularly and occasionally lift 0-15 pounds.
About Catalent

Catalent is a global, high-growth, public company and a leading partner for the pharmaceutical industry in the development and manufacturing of new treatments for patients worldwide. Our mission is to help people live better, healthier lives.

We offer a dynamic, fast-paced work environment, a diverse and inclusive culture, and a range of benefits, including 152 hours of PTO, 8 paid holidays, and a generous 401K match. We are committed to a Patient First culture through excellence in quality and compliance, and to the safety of every patient, consumer, and Catalent employee.

Join us in making a difference and advancing new medicines from early development to clinical trials and to the market. Catalent is an Equal Opportunity Employer, including disability and veterans.



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