Senior Scientist I, Process Analytics Expert

2 weeks ago

South San Francisco, California, United States AbbVie Full time
Job Summary

We are seeking a highly skilled Senior Scientist I to join our Biologics CMC Development team at AbbVie in the Bay Area. The successful candidate will be responsible for providing enhanced understanding of cell line, upstream, and downstream processes through the application of data-rich, high-throughput, rapid-turnaround analytics and automation.

Key Responsibilities
  • Conceive and develop innovative, data-rich, high-throughput, and automated in-process analytical methods and workflows to enable and enhance process understanding and process development efficiency.
  • Perform analytical testing of process intermediates using LCMS peptide mapping, mass spectrometry, U/HPLC, capillary electrophoresis, ELISA, and automation.
  • Collaborate closely with Cell Line Development and Process Development scientists to plan and execute analytical testing for process development experiments.
  • Interpret and communicate in-process analytical results to cross-functional collaborators and stakeholders in a manner that informs cell line selection and process development decisions.
  • Collaborate and communicate effectively with Analytical Molecule Leads to provide data and results from in-process testing for consideration in the context of the overall Analytical Development/QC control strategy.
  • Engage with analytical subject matter experts (SME) to investigate in-process findings that warrant further interrogation with advanced extended characterization methodologies.
  • Work efficiently, collaboratively, and cross-functionally toward project timelines and goals.
  • Serve as an SME for in-process analytics on cross-functional teams.
  • Document laboratory work according to good documentation practices.
Requirements
  • Ph.D. in analytical chemistry, chemistry, biochemistry, or related field. MS and BS candidates with minimum of 8 years (MS) or 10 years (BS) of relevant industry experience and strong record of technical achievement and innovation will also be considered.
  • Expertise with at least one of the following technologies: MAM, LCMS peptide mapping, mass spectrometry, U/HPLC, capillary electrophoresis, ELISA, QPCR, and optical plate reader assays.
  • Demonstrated 'super-user' level experience developing complex methods, as listed above, on integrated liquid handling automation systems in collaboration with colleagues such as SME's and automation engineers.
  • Focus on sustained analytical throughput and data quality in a development or production environment including control strategies such as continuous improvement, control charting, and CAPA.
  • Has independently managed on-going deliverables and timelines for analytical testing projects.
  • Has championed efficient lab and end-user centric ELN/LIMS solutions for data capture, metadata capture, and reporting.
  • General understanding of CMC Analytical Development of protein therapeutics is desired.
  • Experience in application of analytical methods to characterize process development in multi-step biological workflows is a bonus.
  • Pluses includes background in DOE, statistical methods, and data visualization.
  • Proven ability to develop innovative solutions to difficult technical challenges to achieve project goals.
  • Must have effective communication skills, including verbal, written, and scientific data presentation.
  • Must be forward-thinking and able to lead and contribute to scientific/technical discussions.
  • Ability to independently learn, understand and execute novel/advanced scientific techniques.
  • Ability to author technical reports and presentations.
  • Must have ability to work collaboratively with a high degree of productivity in a dynamic, fast-paced, cross-functional environment.

  • Senior Scientist, Analytical Development Expert

    1 month ago

    South San Francisco, California, United States Meet Full time

    Senior Scientist, Analytical Development OpportunityMeet is partnering with a leading Bay Area Biotech to fill a Senior Scientist, Analytical Development position.This exciting opportunity is for a candidate with expertise in small molecule analytical development of drug substances and drug products, with strong CMC experience and CMO oversight to advance...

  • Senior Scientist II, Protein Analytical Chemistry Expert

    1 week ago

    South San Francisco, California, United States AbbVie Full time

    Job DescriptionAbbVie is a leading biopharmaceutical company dedicated to discovering and delivering innovative medicines and solutions that address serious health issues. We are seeking a highly skilled Senior Scientist II to join our Biologics CMC Analytical Research and Development Group in South San Francisco.This is an exciting opportunity to contribute...

  • Senior Data Scientist

    2 weeks ago

    San Francisco, California, United States Gap, Inc. Full time

    Job Title: Senior Data ScientistJoin our team of data science experts at Gap Inc. and contribute to shaping the company's inventory management strategy through advanced data science and forecasting techniques.About the Role:We are seeking a highly skilled Senior Data Scientist to join our Forecasting Team. As a key member of the team, you will be responsible...

  • Senior Scientist, Translational Medicine Expert

    1 month ago

    San Francisco, California, United States Genentech Full time

    Job OpportunityWe are seeking a highly skilled Senior/Principal Scientist to lead lab-based translational research and discovery efforts in the clinical proteomics and mass spectrometry laboratory at Genentech.Key ResponsibilitiesDesign and execute mass spectrometry/clinical proteomics experiments to explore novel biomarker hypotheses and collaborate with...

  • Senior Data Scientist

    1 month ago

    San Francisco, California, United States Unreal Gigs Full time

    Job Title: Senior Data ScientistAt Unreal Gigs, we're seeking a highly skilled Senior Data Scientist to lead our data science initiatives and drive business value through advanced analytics and machine learning.Job SummaryWe're looking for a seasoned data scientist with a strong background in machine learning, statistics, and data visualization. As a Senior...

  • Data Scientist and Analytics Expert

    4 weeks ago

    San Francisco, California, United States Anthropic Full time

    About AnthropicAnthropic is a cutting-edge technology company dedicated to developing safe and beneficial artificial intelligence systems. Our mission is to create AI that is not only intelligent but also interpretable, steerable, and trustworthy.Job DescriptionWe are seeking a highly skilled Data Scientist and Analytics Expert to join our team. As a key...

  • Senior Scientist, Translational Medicine Expert

    1 month ago

    San Francisco, California, United States Genentech Full time

    The OpportunityWe are seeking a highly skilled Senior/Principal Scientist to lead lab-based translational research and discovery efforts in the clinical proteomics and mass spectrometry laboratory at Genentech.This is a hands-on, lab-based position that requires close collaboration with colleagues and departments across multiple functions in Genentech...

  • Scientist I

    2 weeks ago

    South San Francisco, California, United States Planet Pharma Full time

    Job Title: Scientist IPlanet Pharma is seeking a highly motivated and experienced Scientist I to join our Flow Lab team in managing the day-to-day activities of the Flow Cytometry Core Lab.Key Responsibilities:Operate and maintain flow cytometer instruments, ensuring optimal performance and troubleshooting as needed.Implement routine quality control and...

  • Senior Data Scientist

    6 days ago

    San Francisco, California, United States Fractal, Inc. Full time

    Job Title: Senior Data ScientistAt Fractal, Inc., we're seeking a highly skilled Senior Data Scientist to join our team. As a key member of our data science team, you will be responsible for developing and implementing data-driven solutions to drive business growth and improve customer experiences.Key Responsibilities: Develop and maintain large-scale data...

  • Translational Research Scientist

    1 month ago

    South San Francisco, California, United States Pyramid Consulting, Inc Full time

    Job Title: Translational Research Scientist - IWe are seeking a highly skilled Translational Research Scientist - I to join our team at Pyramid Consulting, Inc. in South San Francisco, CA. This is a 12+ months contract opportunity with long-term potential.Job Summary:The successful candidate will work in a multidisciplinary, highly collaborative discovery...

  • Senior Scientist, Drug Product Process Science Specialist

    2 weeks ago

    South San Francisco, California, United States Allogene Therapeutics Full time

    Allogene Therapeutics is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR TTM) products for cancer and autoimmune disease.The company is seeking a highly motivated individual for the role of Senior Scientist, Drug Product Process Science to join the Process and Product Development...

  • Senior/Principal Scientist, Translational Medicine Expert

    2 weeks ago

    San Francisco, California, United States Genentech Full time

    Job OpportunityWe are seeking a highly motivated and experienced Senior/Principal Scientist to lead lab-based translational research and discovery efforts in the clinical proteomics and mass spectrometry laboratory.Key ResponsibilitiesDesign and execute mass spectrometry/clinical proteomics experiments to explore novel biomarker hypotheses and collaborate...

  • Senior Scientist

    2 weeks ago

    San Francisco, California, United States Meet Full time

    Meet is partnering with a leading Bay Area biotech to fill a Senior Scientist, Analytical Development position.This exciting opportunity is for a candidate with expertise in small molecule analytical development of drug substances and drug products, with strong CMC experience and CMO oversight to advance drug candidates through clinical phases to...

  • Senior Bioconjugation Scientist

    2 weeks ago

    South San Francisco, California, United States Global Channel Management Full time

    Bioconjugation Large Molecule Discovery RoleWe are seeking a highly skilled Senior Bioconjugation Scientist to join our team at Global Channel Management.Key Responsibilities:Design and execute experiments to develop and optimize bioconjugates using various conjugation chemistries.Collaborate with cross-functional teams to develop and implement ADC...

  • Research Scientist

    2 weeks ago

    San Francisco, California, United States Swish Analytics Full time

    Research & Experimentation ScientistSwish Analytics is seeking a highly skilled Research & Experimentation Scientist to accelerate progress on our sports betting algorithms and models for increased accuracy and state-of-the-art performance.Key Responsibilities:Experiment with new ideas to create new tools, new feature sets, and reduce latency.Examine the...

  • Research Scientist

    2 weeks ago

    San Francisco, California, United States Swish Analytics Full time

    Research ScientistSwish Analytics is seeking a highly skilled Research Scientist to accelerate progress on our sports betting algorithms and models for increased accuracy and state-of-the-art performance.The ideal candidate will have a strong background in machine learning and data science, with experience in developing and deploying scalable models. They...

  • Senior Formulation Scientist

    5 days ago

    South San Francisco, California, United States Cypress HCM Full time

    Cypress HCM is seeking a highly skilled Senior Formulation Scientist to join our team. As a key member of our formulation development team, you will be responsible for executing experiments for the formulation and QC of oral and parenteral vehicles for in vivo evaluation of novel lead materials.Key Responsibilities:Execute experiments for the formulation and...

  • Scientist II

    1 month ago

    South San Francisco, California, United States Encoded Therapeutics Full time

    Job OverviewEncoded Therapeutics is a biotechnology company advancing precision medicines for a broad range of genetic disorders. We are seeking a highly skilled Scientist II to join our Downstream Process Development team.Key ResponsibilitiesDesign, develop, and optimize purification processes for AAV-based therapeutic candidatesCollaborate with...

  • Senior Clinical Laboratory Scientist

    2 weeks ago

    South San Francisco, California, United States Kaiser Permanente Full time

    Job Summary:We are seeking a highly skilled Senior Clinical Laboratory Scientist to join our team at Kaiser Permanente. As a key member of our laboratory team, you will be responsible for performing pre-analytical, analytical, and post-analytical procedures and analyses to provide data for health maintenance, diagnoses, treatment, and monitoring of medical...

  • Data Scientist

    3 weeks ago

    San Francisco, California, United States Swish Analytics Full time

    Job Title: Research & Experimentation ScientistSwish Analytics is seeking a highly skilled Research & Experimentation Scientist to accelerate progress on our sports betting algorithms and models for increased accuracy and state-of-the-art performance.Key Responsibilities:Experiment with new ideas to create new tools, new feature sets, and reduce...