Senior Scientist
17 hours ago
We are seeking a highly skilled Senior Scientist to join our team at IntegerBio, a cutting-edge biotech company based in the biotech corridor of Montgomery County, Maryland. Our company is dedicated to advancing innovative scientific assets from the lab into the clinic, harnessing the emerging science of immunovirology to create a future free from viral illness.
The successful candidate will bring strong technical skills, meaningful industry experience, and a collaborative approach to cutting-edge scientific research. As a Senior Scientist, you will play a key role in our scientific team, working on protein engineering and antibody discovery capabilities to effectively prosecute our scientific assets.
Key Responsibilities:
- Humanize antibodies using CDR grafting and framework engineering.
- Perform antibody affinity maturation.
- Perform Fc engineering for effector function manipulation and half-life extension.
- Stability engineering of antibodies.
- Engineer antibody mimetics.
- Provide antibody developability analysis.
- Execute strategies for antibody optimization efforts employing advanced molecular biology, biochemistry, cell biology techniques, protein analytics, and modeling bioinformatics.
- Develop processes and assays to discover, generate, and characterize antibodies against selected target antigens.
Requirements:
- PhD in Molecular Biology, Immunology, Biochemistry, or other relevant fields with 3+ years of postdoctoral experience.
- Experience and expertise in therapeutic antibody discovery and engineering with a strong publication record.
- Strong hands-on molecular biology experience is required.
- Expertise in phage display and combinatory library technology.
- Experience in antibody expression and purification is a plus.
- Experience in mentoring, training, and managing others.
IntegerBio is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity, or expression, or any other characteristic protected by federal, state, or local laws.
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