Principal Scientist, Early Discovery Biology
1 week ago
Montai Therapeutics, a pioneering biotechnology company, is seeking an experienced immunologist to join its Early Discovery Biology team. As a key member of this team, you will drive early discovery programs from project conception to hit-to-lead, leveraging our proprietary AI/ML platform to deliver clear decision-making data packages.
Key Responsibilities:- Provide strategic and technical oversight of in vitro screening and hit-to-lead programs with external research partners at CROs
- Analyze and compile screening data into Montai databases, and communicate results to diverse stakeholders to drive project decisions and progression
- Provide immunology subject matter expertise to support broader efforts in target & indication prioritization, experimental approaches and project strategy
- Prepare, review and present scientific presentations for internal/external use
- Work effectively with the leadership team to ensure timely advancement of projects to meet timelines
- PhD in immunology or a related scientific discipline with drug-discovery experience in inflammatory and immunological diseases
- 8+ years of industry experience in small molecule drug discovery-related activities, with experience in small start-up preferred
- Significant experience independently managing external research projects with CROs
- Extensive experience with high-throughput screening methodologies and data analysis
- Strong expertise and research track record in innate and adaptive immune biology, signaling pathways, and immune functions in healthy and diseased states including chronic inflammatory and autoimmune conditions
- Excellent ability to efficiently communicate (written and verbally) complex and technical content to diverse stakeholders
- Self-starter who thrives in collaborative interdisciplinary teams, is unafraid to ask difficult questions, is eager to learn new biology/technology and is passionate about delivering medicines to patients suffering with chronic diseases
Montai Therapeutics is a privately held, early-stage biotechnology company developing a platform for understanding and leveraging complex molecular interactions within organisms to solve global challenges in human health and sustainability. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
-
Principal Scientist, Discovery Biology
2 days ago
Cambridge, Massachusetts, United States Flagship Ventures Full timeTransforming Drug Discovery with Flagship PioneeringAt Flagship Pioneering, we are dedicated to transforming drug discovery by leveraging deep biological insights and cutting-edge scientific innovations. Our mission is to deliver breakthrough therapies that address critical unmet medical needs.Job SummaryWe are seeking an experienced and highly motivated...
-
Principal Research Scientist, Early Discovery
1 month ago
Cambridge, Massachusetts, United States Flagship Ventures Full timeJob SummaryWe are seeking an experienced and highly motivated Principal Scientist with a proven track record of early discovery and characterization of novel biologics to join our team at Flagship Ventures.Key ResponsibilitiesConduct impactful research and experiments for biologics discovery and advancement of our platform.Influence the direction of...
-
Research Scientist
1 month ago
Cambridge, Massachusetts, United States Sunrise Systems Inc Full time**Job Summary**Sunrise Systems Inc is seeking a highly motivated Associate Research Scientist to support our Discovery Biology research programs at our facility. The ideal candidate will contribute to our discovery pipeline from the bench by taking responsibility for developing, optimizing, and troubleshooting cellular assays to characterize and advance our...
-
Research Scientist
1 month ago
Cambridge, Massachusetts, United States Sunrise Systems Inc Full time**Job Summary**Sunrise Systems Inc is seeking a highly motivated Associate Research Scientist to support our Discovery Biology research programs at our facility. The ideal candidate will contribute to our discovery pipeline from the bench by taking responsibility for developing, optimizing, and troubleshooting cellular assays to characterize and advance our...
-
Senior/Principal Scientist, Biology
1 week ago
Cambridge, Massachusetts, United States Crossbow Therapeutics, Inc Full timeAbout the OpportunityCrossbow Therapeutics, Inc. is a biotechnology company dedicated to improving the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. Our T-BoltTM therapies are next-generation, easily assembled immunotherapies directed with high precision at previously unreachable cancer cell...
-
Cambridge, Massachusetts, United States Flagship Pioneering Full timeCompany Overview:Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. With a proven track record of success, Flagship has originated and fostered over 100 scientific ventures, resulting in over $90 billion in aggregate...
-
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob SummaryWe are seeking a highly driven professional with a strong cancer biology background and track record of successfully leading small molecule drug discovery projects from early to development candidate stage. The individual will play a key role in advancing drug discovery programs as well as leading initiatives towards the inception and development...
-
Principal Scientist, Discovery Chemistry
3 days ago
Cambridge, Massachusetts, United States Sarepta Therapeutics Full timeAbout the RoleSarepta Therapeutics is seeking a highly skilled and experienced scientist to join our dynamic and fast-paced chemistry team in Cambridge, MA. As a Principal Scientist, Discovery Chemistry, you will play a key role in our RNA research group, working on our PMO oligonucleotide platform and discovery research on improved delivery of...
-
Cambridge, Massachusetts, United States GSK Full timeJob SummaryWe are seeking a highly skilled Principal Scientist to join our Mammalian Expression Technology Center of Excellence (MET CoE) team in Cambridge, MA. As a Principal Scientist, you will be responsible for driving the design, development, and implementation of in-process analytical methods to support cell line and early process development...
-
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob SummaryWe are seeking a highly driven professional with a strong cancer biology background and track record of successfully leading small molecule drug discovery projects from early to development candidate stage. The individual will play a key role in advancing drug discovery programs as well as leading initiatives towards the inception and development...
-
Cambridge, Massachusetts, United States Novartis Full timeAbout the RoleWe are seeking a highly driven professional with a strong cancer biology background and track record of successfully leading small molecule drug discovery projects from early to development candidate stage. The individual will play a key role in advancing drug discovery programs as well as leading initiatives towards the inception and...
-
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob DescriptionJob Summary:We are seeking a highly driven professional with a strong cancer biology background and track record of successfully leading small molecule drug discovery projects from early to development candidate stage.About the Role:The individual will play a key role in advancing drug discovery programs as well as leading initiatives towards...
-
Principal Research Scientist
3 weeks ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeAbout the Role:We are seeking a highly motivated and creative Principal Scientist to join our interdisciplinary team that combines chemical biology, covalent drug discovery, mass spectrometry, cell biology, and informatics technologies to tackle the challenge of identifying covalent small molecules that modulate the activity of undrugged targets and...
-
Principal Scientist, Discovery Chemistry
6 days ago
Cambridge, Massachusetts, United States Sarepta Therapeutics Full timeAbout the RoleSarepta Therapeutics is seeking a highly skilled and experienced scientist to join our RNA Research group in Cambridge, MA. As a Principal Scientist, Discovery Chemistry, you will be responsible for designing and conducting novel oligonucleotide conjugates synthesis, purification, and characterization. You will also apply state-of-the-art...
-
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob Opportunity SummaryWe are seeking a highly driven professional with a strong cancer biology background and track record of successfully leading small molecule drug discovery projects from early to development candidate stage.Key Responsibilities:Lead and mentor a team of scientists in oncology drug discovery and early development, with a focus on small...
-
Senior Principal Scientist, Pharmacology
2 weeks ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeAbout the Role:The Novartis Group of Companies is seeking a highly skilled and experienced Senior Principal Scientist to join our team in Cambridge, MA. As a key member of our dynamic and multi-disciplinary team, you will play a critical role in developing and applying in vivo models to evaluate novel cancer therapies in the early-stage drug discovery...
-
Senior Scientist, Discovery Program Lead
4 weeks ago
Cambridge, Massachusetts, United States CAMP4 Therapeutics Full timeAbout the RoleCAMP4 Therapeutics is seeking a highly skilled and experienced scientist to lead our Discovery team in driving cutting-edge projects from target selection through development candidate selection. As a Principal Scientist, Discovery, you will be responsible for driving innovative science to develop antisense oligonucleotide drugs against...
-
Principal Scientist, Medicinal Chemistry Expert
4 weeks ago
Cambridge, Massachusetts, United States Flagship Ventures Full timeTransform Human Health and SustainabilityFlagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. We are seeking a talented and highly motivated Principal Scientist, Medicinal Chemistry to join our team.Key ResponsibilitiesDesign and...
-
Cambridge, Massachusetts, United States Flagship Pioneering Full timeAbout the RoleWe are seeking a highly skilled and motivated Translational Multiomics Scientist to join our team at Flagship Pioneering. As a key member of our biomarker discovery and data analysis team, you will play a critical role in developing and applying computational skills to understand complex biological systems and their relationship to clinical...
-
Principal Scientist, Molecular Biology
4 weeks ago
Cambridge, Massachusetts, United States Generation Bio Full timeJob Summary:Generation Bio is seeking a highly motivated and experienced molecular biologist to join our team as a Principal Scientist. The successful candidate will have a strong background in mammalian cellular trafficking and a deep understanding of nuclear pore complex structure and function.Key Responsibilities:Design and optimize nuclear translocation...
