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Molecular Biology Research Associate
2 months ago
Position Overview
Location: San Diego, CA
About the Opportunity:
We are in search of a dedicated and skilled Molecular Biology Research Associate to become a vital part of our innovative in vitro pharmacology team. This role focuses on pioneering advancements in gene therapy and siRNA applications for neurological and neuromuscular disorders. As an integral member of our research unit, you will contribute significantly to various research initiatives, including the processing of tissue samples, conducting biodistribution studies, developing biomarker assays, and managing antibody screening efforts. Join us in our commitment to revolutionizing treatment options for patients suffering from neurological and neuromuscular conditions through state-of-the-art gene therapy methodologies.
Your Core Responsibilities:
- Provide comprehensive molecular biology support across programs, including biodistribution assessments and quality control to validate reagents, vectors, and construct designs.
- Perform tissue sample processing techniques for the isolation of DNA, RNA, and proteins for subsequent analyses.
- Conduct gene expression evaluations using methodologies such as RT-/ddPCR and ELISA assays, along with RNAseq library preparation and other molecular biology tasks as required.
- Assist in the development of in vitro bioassays within engineered cell lines and disease-relevant in vitro models.
- Offer administrative and operational assistance to the In Vitro Pharmacology team, including procurement processes, database management, and laboratory oversight.
- Plan, execute, and analyze experiments under guidance while maintaining meticulous documentation of findings.
- Manage vendor interactions effectively.
- Ensure a safe laboratory environment and adhere to good laboratory practices.
- Collaborate within a dynamic, cross-functional scientific environment.
Qualifications:
Essential Qualifications:
- Bachelor's degree in molecular biology, cell biology, biochemistry, bioengineering, or a related scientific field with no prior experience required.
- Familiarity with fundamental molecular biology techniques, including cloning, DNA/RNA isolation, and PCR.
- Experience with basic protein assay techniques, such as Western blotting and ELISA.
- Knowledge of essential cell biology methods, including aseptic cell culture, cell counting, and cell banking.
- Exposure to gene therapy and biodistribution techniques is advantageous.
- Ability to quickly learn new methodologies.
- Strong organizational capabilities and a solid work ethic.
Desirable Qualifications:
- Previous experience in gene therapy research, particularly focused on neurological and neuromuscular conditions.
- Proven ability to thrive in a fast-paced, collaborative team environment and prioritize tasks across multiple projects.
- Reliability and a strong orientation towards achieving goals and meeting deadlines.
- Hands-on experience with automation and high-throughput screening systems is a plus.
Why Choose Novartis:
At Novartis, we believe that addressing the needs of patients and their families requires more than just innovative science. It demands a community of intelligent, passionate individuals like you, who collaborate, support, and inspire one another to achieve breakthroughs that can transform patients' lives.
Commitment to Diversity & Inclusion:
The Novartis Group of Companies is an Equal Opportunity Employer, dedicated to fostering a diverse environment. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices based on race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams that reflect the patients and communities we serve, striving to create an inclusive workplace that encourages bold innovation through collaboration and empowers our employees to reach their full potential.
Accessibility and Reasonable Accommodations:
The Novartis Group of Companies is committed to working with and providing reasonable accommodations to individuals with disabilities. If you require assistance during the application process or need accommodations to perform essential job functions, please reach out to us to discuss your needs.
Salary Range:
$80,000 - $120,000
Desired Skills:
Analytical Skills, Laboratory Techniques, Collaboration, Communication Skills, Data Analysis, Problem Solving, and more.
