Research Fellow in Chemical Biology

1 week ago


Cambridge Massachusetts, United States Biogen Full time
About the Role

We are seeking a highly motivated Research Fellow to join our Chemical Biology and Proteomics group at Biogen. As a Research Fellow, you will have the opportunity to design, develop, and apply existing and new target identification strategies to various drug discovery programs.

Key Responsibilities
  • Develop and utilize chemical biology methods for target identification, target engagement, and selectivity profiling studies to elucidate the mechanism of action of small molecule drug candidates.
  • Use chemoproteomics to investigate cysteine reactivity, oxidation, and ligandability in neurodegenerative diseases.
  • Design and apply chemical probes for cellular protein activity profiling.
  • Conduct small molecule probe experiments in mammalian cell culture and tissue homogenate and analysis of these samples using a variety of protein detection methods including in gel fluorescence, Western blotting, and mass spectrometry.
  • Present at both internal and external meetings and publish.
Requirements

You are a recent Ph.D. graduate with a background in chemical biology, proteomics, chemistry, or biochemistry who is self-motivated and eager to make impactful contributions to drug discovery. You will be expected to work with cross-functional teams.

About Biogen

Biogen is one of the world's leading biopharmaceutical companies, with a focus on developing therapies for serious neurologic diseases. We are committed to research that uncovers the underlying biology of complex diseases.



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