Senior Manager, Real-World Evidence for Vaccines
2 weeks ago
POSITION OVERVIEW
The Global Scientific Affairs team focused on COVID-19 and influenza is at the forefront of generating evidence for vaccines, therapeutics, and diagnostics. Within this team, a specialized group of Real-World Evidence (RWE) Scientists, reporting to the COVID & Flu Databases Team Lead, is responsible for developing and executing evidence generation strategies utilizing internal databases to support COVID and flu vaccine initiatives, antiviral treatments, and diagnostic tools. The Senior Manager will be instrumental in providing timely feasibility evaluations, rapid real-world insights (RWI), and concise summary reports by aligning with stakeholder goals and timelines. They will also contribute to and occasionally lead the creation of RWE protocols in collaboration with cross-functional asset teams and Biostatistics to demonstrate and enhance the value of all assets.
The Senior Manager will act as a subject matter expert on data sources, offering guidance on the most suitable types of data, datasets, innovative methodologies, and algorithms for specific challenges. They will coordinate RWE project execution with relevant internal and partner analytic resources and tools, ensuring the establishment of consistent business rules, versioning protocols as care pathways evolve, and adherence to standards and procedures.
This role is pivotal in delivering in-house RWE projects and supporting the strategic development of vaccines and antiviral initiatives to adapt to the evolving landscape of real-world evidence.
KEY RESPONSIBILITIES
- Lead RWI for feasibility evaluations, go/no-go decisions, and co-design dashboards to inform cross-functional teams' hypothesis generation, providing timely and detailed insights.
- Collaborate with team members to foster strong internal and external partnerships, serving as a subject matter expert by offering consultations on all aspects of RWD studies and analyses, including feasibility assessments, objectives, study design, data source identification, protocol development, statistical analyses, and table shells.
- Support the enhancement of RWD and analytics capabilities, applying advanced analytics methodologies, analysis tools, and visualization platforms to generate novel insights and actionable outcomes.
- Conduct and oversee rapid RWD-based queries and studies, effectively communicating findings and results to internal stakeholders through tables, visualizations, concise reports, and presentations.
- Contribute to and/or lead external publications, including conference abstracts, posters, and manuscripts.
- Establish standards and processes to manage the quality, consistency, usability, security, and availability of data throughout its lifecycle; remain updated on RWD/E best practices.
- Coordinate and drive internal cross-functional teams, Biostatistics, and other colleagues to create high-quality RWE from rigorously designed protocols.
- Partner with various stakeholders, including pipeline/asset teams, RWE Operations Leads, Biostatistics, and Digital RWD, to collaboratively develop high-quality methods, innovative approaches, protocols, and designs.
- Contribute to asset medical strategy and evidence generation planning.
- Identify opportunities to automate processes and create efficiencies, harmonizing rules with other analysis teams, and integrating all deliverables into the Digital RWD knowledge and insights management system.
- Assess vendor due diligence for potential partnerships or new data/technology sources as directed.
- Document all requests and track progress toward project completion, creating and measuring quarterly ROI metrics to ensure alignment with business goals.
BASIC QUALIFICATIONS
The ideal candidate will possess a Master's degree with over 5 years of experience or a PhD with over 2 years in RWE analytics or related fields such as Nursing, Biomedical Informatics, Public Health, HEOR, Epidemiology, or other quantitative and computational disciplines. A proven track record in scientific analysis of real-world data for various purposes is essential.
- Knowledge of Electronic Health Records, medical and pharmacy claims, patient registries, and other real-world data sources.
- Advanced understanding of pharmacoepidemiologic methods and study design.
- Strong communication skills, both verbal and written, with the ability to present complex information clearly to diverse audiences.
- Quality-focused, organized, and capable of working under pressure with a high level of autonomy.
- Experience in protocol development and execution for non-interventional studies using various analytical techniques.
- Significant hands-on experience analyzing multiple types of real-world data, including EHR, claims, registry data, and laboratory results.
PREFERRED QUALIFICATIONS
- 3+ years of experience in real-world data analytics within healthcare, clinical research, or life sciences.
- Knowledge of vaccine development, infectious diseases, and immunology is highly desirable.
- Understanding of global regulatory guidance for RWE submission is preferred.
- Experience with clinical registries and patient-generated health data is advantageous.
- Ability to manage teams and lead through influence in a matrixed environment.
- Skills in managing and analyzing large databases, including data visualization and exploratory data analysis.
ADDITIONAL REQUIREMENTS
The role may require periodic travel.
COMPENSATION AND BENEFITS
The annual base salary for this position ranges from $131,200.00 to $218,000.00, with eligibility for participation in Pfizer's Global Performance Plan and comprehensive benefits to support employees' health and well-being.
EEO & EMPLOYMENT ELIGIBILITY
Pfizer is committed to equal opportunity in employment and complies with all applicable laws governing nondiscrimination.
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