Director, Translational Medicine Leader

3 weeks ago

Rockville, Maryland, United States Otsuka Full time
Job Summary

Otsuka Pharmaceutical Company is a global healthcare leader with a strong commitment to innovation and patient-centricity. We are seeking a highly skilled Director, Translational Medicine to join our team and contribute to the development of novel CNS assets.

Key Responsibilities
  • Lead discovery and translational efforts related to CNS target identification, lead identification through IND and proof-of-concept.
  • Collaborate with internal and external groups to provide CNS translational expertise in the evaluation of molecular and biological targets, new compounds, as well as new formulation technologies.
  • Partner with internal and external research organizations to expand and facilitate progression/development of discovery and early phase CNS compounds.
  • Represent TM in cross-functional as well as internal/external collaborations (BD, MSRD, etc.) on activities related to early phase target and asset identification.
  • Provide expert advice to internal discovery teams as well as external and early investment partners on go/no go decisions for CNS assets in lead optimization and early development.
  • Serve as the TM Lead for pre-clinical/discovery stage and early phase assets and provide technical, scientific expertise to development plans.
  • Provide TM expertise and interact with subject matter experts to support translational plans leading to go/no go decisions on discovery as well as early phase assets.
  • Support public/private partnerships in the pre-competitive space to promote advancement of capabilities of emerging translational medicine initiatives.
Requirements
  • MD or PhD in Pharmacology, Physiology/Biology (or a related area) with a minimum of 10 years of experience in a Translational Medicine group is required.
  • Must be able to apply scientific knowledge (in the areas specified above) to further the company's assets, anticipate and identify core problems, apply insightful analysis, and solve problems effectively.
  • Leadership experience related to Early Phase and Translational Medicine.
  • Strong organization skills.
  • Clear, concise, and persuasive communication.
  • Flexibility to react rapidly to changing situations/environment.
Preferred Qualifications
  • Subject matter expertise across several CNS biomarkers, translational tools and technologies (e.g., PET, fMRI, EEG, behavioral and/or neuro-/psycho-physiological approaches).
  • Demonstrated discovery and early phase clinical development experience within the field of Neuropsychopharmacology.
  • Integrated working knowledge of translational medicine and its application/deployment to address GO/NOGO decisions in drug discovery, and early phase clinical development.
  • Detailed knowledge of the regulatory path for early phase assets and familiarity with the prevailing, contemporary regulatory guidance documents as applied to translational studies of early phase assets.
  • Demonstrated interpersonal effectiveness in working collaboratively across matrixed teams.
What We Offer
  • Comprehensive medical, dental, vision and prescription drug coverage
  • Company provided Basic Life, AD&D, Short-term and Long-term Disability insurance
  • Tuition reimbursement
  • 401(k) match
  • PTO allotment each calendar year, paid holidays, and paid leave programs as well as other company provided benefits

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