Principal Scientist, Bioprocess Development Specialist
2 weeks ago
UPSIDE Foods is a pioneering company in the field of cultivated meat, dedicated to creating a more sustainable and humane food system. Based in Berkeley, CA, the company has achieved numerous industry-defining milestones, including the production of multiple species of meat and the sale of a cultivated meat product in the United States.
Job DescriptionWe are seeking a highly experienced Principal Scientist, Bioprocess Development to support the scale-up of novel platforms for the cultivation of cultivated meat. The successful candidate will be responsible for leading technology transfer activities, technical support of processes in production, and managing person-in-plant support as part of the Manufacturing Sciences and Technology (MSAT) sub-team with BPD.
Key Responsibilities- Lead technology transfer activities and technical support of processes in production, including managing person-in-plant support as part of the MSAT sub-team with BPD.
- Independently design, oversee, and analyze experiments ranging from bench through pilot scale, leading to process transfer to commercial scale and manufacturing support.
- Drive the evaluation, development, and implementation of new manufacturing technologies.
- Lead new process scale-up, including selection, installation, and evaluation of new bioreactor technologies and development of operating procedures.
- Act as the subject matter technical expert for large-scale animal cell bioprocesses.
- Mentor and lead junior team members to accomplish project goals.
- Support regulatory filings and facility startup as needed.
- A total of 15+ years of experience in mammalian cell culture bioprocess development and process transfer across scales in academic and industry settings.
- Advanced degrees are preferred with a combined equivalent of relevant industrial experience in cell biology, molecular biology, bioengineering, chemical engineering, or related life sciences field.
- Experienced with cGMP operations and/or pilot plant operations with 5+ years management experience leading staff and teams responsible for process development and/or technology transfer and manufacturing support.
- Experience with leading the development and/or tech transfer of upstream bioreactor modes of operations such as fed-batch or perfusion into production with animal or mammalian suspension cells at large scale is required.
- Expertise in development of new bioprocesses, and process transfer to production, including scale-up and scale-down of bioreactors and bioprocess controller systems.
- Ability to relate with people at all levels within an organization, including diverse cultures.
- Comfortable working and mentoring in a team-based environment.
- Must be willing and able to work evenings and weekends when needed.
- Experience in data analysis platforms (e.g. JMP, Minitab), including statistical analysis and presenting data in table and graph forms.
- The BPD team, and especially the MSAT sub-team, interfaces with all aspects of R&D, BPD, and Manufacturing, and this person will accordingly work with stakeholders across the organization to design studies and manage handoffs of materials and data.
- To support tech transfer and manufacturing operations, this person will manage teams responsible for preparing process documentation, transferring processes into manufacturing, and providing on-floor support.
- Work within the MSAT sub-team of BPD to enable tech transfer and support of large-scale bioprocess operations.
- Lead efficient technology transfer workflows.
- Lead dedicated manufacturing support.
- Enable testing of most current processes at bench and pilot scales prior to technology transfer to commercial scales.
- Implement a dedicated pilot-scale suspension production function to support Food R&D prototyping efforts.
UPSIDE Foods offers a competitive compensation package, including stock options, 90-100% employer-paid healthcare premiums, pet insurance, unlimited PTO, and company-sponsored learning and development opportunities.
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Principal Scientist, Bioprocess Development
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