Lead Biologist, GSK Cambridge

6 days ago


Rockville, Maryland, United States GSK LLP Full time

About Us

GSK LLP is a global biopharma company committed to uniting science, technology and talent to get ahead of disease together. Our research and development efforts focus on discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.

Job Description

We are seeking an experienced Principal Scientist, Structural Biology to join our team in Cambridge, MA. The successful candidate will be responsible for designing and implementing procedures to conduct advanced research and experiments utilizing techniques such as X-ray crystallography and cryo-electron microscopy (cryo-EM).

Responsibilities

  • Collaborate with the protein production, molecular design, and biophysics teams to design new constructs and mutants based on structural analysis for all aspects of project progression.
  • Deliver reagents and structural data to impact projects through protein expression & purification, crystal growth & optimization, data collection, and X-ray structure solution experiments.
  • Manage, use, and maintain the equipment in a state-of-the-art crystallization laboratory.
  • Interpret the results of structural and biophysical experiments to inform structure-based drug design.

Requirements

  • PhD in a structural biology related field with a focus on protein crystallography.
  • Three or more years of experience with protein chemistry and structural biology.
  • Ability to design and conduct complex experiments and interpret results.
  • Experience in macromolecular crystallography, including the principles and techniques used in the field.
  • Laboratory experience in protein expression, biochemistry, protein crystallization, and data collection.

Benefits

  • An estimated salary range of $111,350 - $150,650 depending on experience and qualifications.
  • A comprehensive benefits package including health insurance, retirement plan, paid holidays and vacation time.
  • The opportunity to work with a global leader in the pharmaceutical industry.

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