Principal Scientist, Structural Biology Expert
3 weeks ago
About the Role
We are seeking an experienced Principal Scientist, Structural Biology to join our team at GSK LLP. As a key member of our research team, you will be responsible for leading structural biology projects and collaborating with cross-functional teams to design and develop innovative solutions.
Key Responsibilities
- Design and implement procedures to conduct advanced research and experiments utilizing techniques such as X-ray crystallography and cryo-electron microscopy (cryo-EM), to determine the three-dimensional structures of proteins and protein complexes.
- Collaborate with the protein production, molecular design, and biophysics teams to design new constructs and mutants based on structural analysis for all aspects of project progression.
- Deliver reagents and structural data to impact projects through protein expression & purification, crystal growth & optimization, data collection, and X-ray structure solution experiments.
- Manage, use, and maintain the equipment in a state-of-the-art crystallization laboratory.
Requirements
- PhD in a structural biology related field with a focus on protein crystallography.
- Three or more years of experience with protein chemistry and structural biology.
- Ability to design and conduct complex experiments and interpret results.
- Experience in macromolecular crystallography, including the principles and techniques used in the field.
- Laboratory experience in protein expression, biochemistry, protein crystallization, and data collection.
Benefits
- An estimated salary range of $111,350 - $150,650 depending on experience and qualifications.
- A comprehensive benefits package including health insurance, retirement plan, paid holidays and vacation time.
- The opportunity to work with a global leader in the pharmaceutical industry.
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