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Director, Medical Affairs Oncology AI Innovation

United States - Washington – Bothell United States - Pennsylvania - Collegeville United States - New York - New York City United States - Massachusetts - Cambridge Today, Pfizer Oncology has an industry-leading portfolio of 25 approved innovative cancer medicines, including major therapies for metastatic breast cancer, prostate cancer, urothelial carcinoma and haemato-oncological malignancies. Pfizer’s in-line portfolio is focused on four broad, key areas: breast cancer, genitourinary cancer, hematology and precision medicine, complemented by an extensive pipeline of over 50 programs in clinical development. The Medical Affairs AI Innovation Director will report into the Oncology AI Innovation Head This is a vital role within the Pfizer Oncology organization, a cting as an operational business partner across Oncology Medical, International Medical Affairs and Pfizer US (Medical Platforms) for all Artificial Intelligence (AI) and digital innovation related initiatives. The successful candidate will be a health technology solutions leader passionate about the potential of AI and digital innovation to transform how Medical can help breakthrough oncology therapies alter clinical practice and transform cancer patients’ outcomes. The incumbent will help to embed a digital AI-first mindset and culture across Oncology Medical teams, enable internal and external collaboration around Medical use cases of AI digital innovation initiatives and lead on external engagement to identify, evaluate, and secure AI digital innovation opportunities for Oncology Medical. They will be responsible for implementing AI digital innovation use cases within Oncology Medical and collaborating with AI Innovation colleagues in other parts of Pfizer to drive forward the digital first agenda across the organization. Example use cases include improved medical landscape sensing, Medical Strategy deliverable production process improvements, Field Medical excellence analytics and Medical content personalization, etc. It is expected that these efforts will provide direct and visible benefits to Pfizer Oncology Medical process efficiency, Medical Strategy generation and execution, and Field Medical effectiveness in the near-, mid-, and long-term. ROLE RESPONSIBILITIES Support the Oncology AI Innovation Head and Oncology Medical leaders in identifying and articulating opportunities for digital

technologies/transformation

to enhance the effectiveness of global Oncology Medical strategy deliverable development execution and US Field Medical effectiveness. Lead as an AI Subject Matter Expert within Oncology Medical, championing AI and innovative technology to achieve goals, inform medical decisions and drive future access for patients in a faster and HCP/patient centric manner. Maintain current knowledge of technology trends and industry solutions with relevance to Medical Strategy and Affairs via market intelligence and strategic vendor partnerships. Work closely with Pfizer Oncology (especially Medical and

Oncology Scientific Affairs and Strategic Partnerships)

and other enterprise teams to identify emerging external AI/digital innovations and technologies. Implementation: Support execution against Pfizer Oncology Medical’s AI breakthrough goals including managing cross-functional teams across Pfizer Oncology Medical, International Medical Affairs, and Pfizer Us (Medical Platforms) including budget monitoring, KPI’s and successful deployment in partnership with Digital. Support the Oncology AI Innovation Head in developing business case / ROI expectations for above innovation opportunities (in partnership with Business Development where relevant) and work with Oncology Medical departmental leaders, Pfizer US (Medical Platforms) colleagues and the Pfizer Oncology LT to obtain Oncology and wider enterprise endorsement and funding for the proposed innovations. Collaborate with colleagues across Pfizer Oncology (especially Medical and

Oncology Scientific Affairs and Strategic Partnerships) , International Medical Affairs, Pfizer US (Medical Platforms) and the broader business, including interacting with machine learning (ML) professionals, data scientists and programmers within AI/Data COEs to lead the implementation of novel AI-enabled Oncology Medical approaches and/or strategic initiatives that enhance the effectiveness of global Oncology Medical strategy deliverable development / execution and US Field Medical effectiveness, as well as providing strategic insight into programs. Support colleagues across Oncology Medical with innovative data/AI/ML solutions to complement and reorganize existing practices - including Identifying recent developments in AI research that may impact Oncology R&D. Support Field Medical excellence through the enablement of AI-driven insight analytics Manage lifecycle of AI digital solutions from concept design, prototyping, to development and release. Work with R&D IT teams to identify and manage data security risks and GxP validation requirements for digital technologies. Serve as Pfizer representative to strategic Medical-relevant AI/digital partnerships with external organizations, healthcare institutions, and tech companies to leverage AI capabilities and stay at the forefront of innovation. Impact: Measure and demonstrate tangible business impact of AI solutions and analyzing data to assess ROI and making data driven decisions to optimize AI strategies for maximum value creation. Drive awareness among Medical teams of the value created / ROI from oncology development-focused AI/digital technological innovation, and work with Oncology Scientific Affairs and Strategic Partnerships colleagues on external communications on these topics. BASIC QUALIFICATIONS Bachelor’s Degree in computer science (or related field) with 10+ years experience in implementation of AI/ML/DL-driven strategies. Deep insights into the biotech / healthcare AI/digital

environment/ecosystem. 5+ years’ experience in driving cross functional teams to develop AI solutions aligned with business goals for maximum impact and successful delivery. 5+ years’ experience in leading AI digital innovation strategies and implementation in the biotech / pharmaceutical R&D or Medical field. Passionate about the application of AI/Gen-AI in healthcare to transform patient outcomes and care. Experience acting as an interface between business and technical delivery teams to originate and implement novel forms of analytics and manage cross-functional innovation projects. Excellent communication, presentation, and interpersonal skills. Ability to work within a matrix organization and collaborate effectively across functions (e.g., R&D, Commercial and IT) Strong demonstrated skills in relevant capabilities such as product development, ecosystem activation, etc. Preferred requirements Experience working in the Oncology therapeutic area. Experience working in Medical Strategy and/or Affairs. Experience working with Design Thinking processes. Strong technical skills including applying and developing methods of algorithms inAI, data sciences best practices, problem solving and analytical thinking. Demonstrated success in developing and executing AI and innovation strategies within biopharmaceutical industry or a similarly highly regulated setting. Job Description

ROLE SUMMARY Today, Pfizer Oncology has an industry-leading portfolio of 25 approved innovative cancer medicines, including major therapies for metastatic breast cancer, prostate cancer, urothelial carcinoma and haemato-oncological malignancies. Pfizer’s in-line portfolio is focused on four broad, key areas: breast cancer, genitourinary cancer, hematology and precision medicine, complemented by an extensive pipeline of over 50 programs in clinical development. The Medical Affairs AI Innovation Director will report into the Oncology AI Innovation Head This is a vital role within the Pfizer Oncology organization, a cting as an operational business partner across Oncology Medical, International Medical Affairs and Pfizer US (Medical Platforms) for all Artificial Intelligence (AI) and digital innovation related initiatives. The successful candidate will be a health technology solutions leader passionate about the potential of AI and digital innovation to transform how Medical can help breakthrough oncology therapies alter clinical practice and transform cancer patients’ outcomes. The incumbent will help to embed a digital AI-first mindset and culture across Oncology Medical teams, enable internal and external collaboration around Medical use cases of AI digital innovation initiatives and lead on external engagement to identify, evaluate, and secure AI digital innovation opportunities for Oncology Medical. They will be responsible for implementing AI digital innovation use cases within Oncology Medical and collaborating with AI Innovation colleagues in other parts of Pfizer to drive forward the digital first agenda across the organization. Example use cases include improved medical landscape sensing, Medical Strategy deliverable production process improvements, Field Medical excellence analytics and Medical content personalization, etc. It is expected that these efforts will provide direct and visible benefits to Pfizer Oncology Medical process efficiency, Medical Strategy generation and execution, and Field Medical effectiveness in the near-, mid-, and long-term. ROLE RESPONSIBILITIES Strategy: Support the Oncology AI Innovation Head and Oncology Medical leaders in identifying and articulating opportunities for digital

technologies/transformation

to enhance the effectiveness of global Oncology Medical strategy deliverable development execution and US Field Medical effectiveness. Lead as an AI Subject Matter Expert within Oncology Medical, championing AI and innovative technology to achieve goals, inform medical decisions and drive future access for patients in a faster and HCP/patient centric manner. Maintain current knowledge of technology trends and industry solutions with relevance to Medical Strategy and Affairs via market intelligence and strategic vendor partnerships. Work closely with Pfizer Oncology (especially Medical and

Oncology Scientific Affairs and Strategic Partnerships)

and other enterprise teams to identify emerging external AI/digital innovations and technologies. Implementation: Support execution against Pfizer Oncology Medical’s AI breakthrough goals including managing cross-functional teams across Pfizer Oncology Medical, International Medical Affairs, and Pfizer Us (Medical Platforms) including budget monitoring, KPI’s and successful deployment in partnership with Digital. Support the Oncology AI Innovation Head in developing business case / ROI expectations for above innovation opportunities (in partnership with Business Development where relevant) and work with Oncology Medical departmental leaders, Pfizer US (Medical Platforms) colleagues and the Pfizer Oncology LT to obtain Oncology and wider enterprise endorsement and funding for the proposed innovations. Collaborate with colleagues across Pfizer Oncology (especially Medical and

Oncology Scientific Affairs and Strategic Partnerships) , International Medical Affairs, Pfizer US (Medical Platforms) and the broader business, including interacting with machine learning (ML) professionals, data scientists and programmers within AI/Data COEs to lead the implementation of novel AI-enabled Oncology Medical approaches and/or strategic initiatives that enhance the effectiveness of global Oncology Medical strategy deliverable development / execution and US Field Medical effectiveness, as well as providing strategic insight into programs. Support colleagues across Oncology Medical with innovative data/AI/ML solutions to complement and reorganize existing practices - including Identifying recent developments in AI research that may impact Oncology R&D. Support Field Medical excellence through the enablement of AI-driven insight analytics Manage lifecycle of AI digital solutions from concept design, prototyping, to development and release. Work with R&D IT teams to identify and manage data security risks and GxP validation requirements for digital technologies. Serve as Pfizer representative to strategic Medical-relevant AI/digital partnerships with external organizations, healthcare institutions, and tech companies to leverage AI capabilities and stay at the forefront of innovation. Impact: Measure and demonstrate tangible business impact of AI solutions and analyzing data to assess ROI and making data driven decisions to optimize AI strategies for maximum value creation. Drive awareness among Medical teams of the value created / ROI from oncology development-focused AI/digital technological innovation, and work with Oncology Scientific Affairs and Strategic Partnerships colleagues on external communications on these topics. BASIC QUALIFICATIONS Bachelor’s Degree in computer science (or related field) with 10+ years experience in implementation of AI/ML/DL-driven strategies. Deep insights into the biotech / healthcare AI/digital

environment/ecosystem. 5+ years’ experience in driving cross functional teams to develop AI solutions aligned with business goals for maximum impact and successful delivery. 5+ years’ experience in leading AI digital innovation strategies and implementation in the biotech / pharmaceutical R&D or Medical field. Passionate about the application of AI/Gen-AI in healthcare to transform patient outcomes and care. Experience acting as an interface between business and technical delivery teams to originate and implement novel forms of analytics and manage cross-functional innovation projects. Excellent communication, presentation, and interpersonal skills. Ability to work within a matrix organization and collaborate effectively across functions (e.g., R&D, Commercial and IT) Strong demonstrated skills in relevant capabilities such as product development, ecosystem activation, etc. Preferred requirements Experience working in the Oncology therapeutic area. Experience working in Medical Strategy and/or Affairs. Experience working with Design Thinking processes. Strong technical skills including applying and developing methods of algorithms inAI, data sciences best practices, problem solving and analytical thinking. Demonstrated success in developing and executing AI and innovation strategies within biopharmaceutical industry or a similarly highly regulated setting. The annual base salary for this position ranges from $161,600.00 to $269,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Marketing and Market Research #J-18808-Ljbffr