Data Scientist

3 weeks ago

Watertown, United States Abata Therapeutics Full time

SCIENTIST, DATA SCIENCES Abata has a big vision focused on translating the biology of regulatory T cells (Tregs) into transformational medicines for patients, particularly in severe autoimmune and inflammatory diseases with inadequate or no therapeutic options. While cell therapies represent a significant advancement in treating human disease, they have not yet been rigorously evaluated and developed for the treatment of autoimmune and inflammatory diseases. The company believes that by engineering Tregs for targeted activation only at the site of disease, enabling a robust, durable response, while avoiding systemic immune suppression, they can revolutionize the treatment of these challenging chronic diseases. Our work is transformative which is why we hire the best, brightest, and most importantly…kind people. Being kind is not just a personality trait we look for, it’s a core value , embedded in the way we work and how we shape your experience at Abata Therapeutics. One of the most important aspects of your experience at Abata is how you develop and grow with the company. Our culture of learning and growth enables everyone to do their best work and contribute to fulfilling our mission. The Role: Abata is currently searching for a highly skilled Data Sciences specialist to play a pivotal role in advancing the development of groundbreaking therapeutics. Collaborating closely with research, development, translational, and clinical teams, the successful candidate will spearhead the creation of cutting-edge omics technologies and strategically apply them to early discovery and translational development processes. This role demands a dynamic individual with a passion for pushing the boundaries of data sciences in the realm of healthcare, contributing to the evolution of innovative solutions in the field. If you are driven by the prospect of influencing the future of therapeutic development through data-driven insights, we invite you to join our team at Abata. Major Responsibilities: ·Lead computational biology across all programs to support TCR discovery and Treg production. ·Develop and optimize TCR analysis capabilities ·Interpret scRNAseq, DNA-methylation, and related genomic data, integrating both public and proprietary data ·Collaborate cross-functionally to contribute to hypothesis-driven science ·Build bioinformatics pipelines for characterizing the TCR-repertoire from high throughput single cell sequencing assays ·Communicate and explain computational models and machine learning techniques to ensure collaborators understand capabilities, limitations and assumptions behind algorithms and methodologies Requirements and Qualifications · PhD in Computational Biology, Bioinformatics, Genetics, Biophysics, Machine Learning, or BS/ MS and 5-8 years of experience · 2 plus year biotech experience preferred · Bonus: experience in T cell immunology or immunoglobulin sequencing · Experience with common bioinformatics tools and pipelines · Experience with commonly used machine learning algorithms and tool sets · Familiarity with concepts, techniques, and common tools used for sequence analysis and protein structure modeling. · Experience with Unix/Linux, HPC environments, and high-level commonly used data science programming languages (e.g. R, Python). · Excellent communication and interpersonal skills.

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