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Research Scientist III LC/MS

1 month ago


Jackson, United States Sikla Full time

Research Scientist III LC/MS -Contract - Lexington MA Ƶ is seeking a dedicated and innovative LC-MS Analytical Scientist. Primary Responsibilities: The successful candidate will focus on developing advanced LC-MS analytical methods for bioanalysis of various molecular formats. This role also involves maintaining lab instruments and supporting the team's knowledge through scientific literature updates and discussions. Skills & Requirements: PhD or Master's degree in pharmaceutical sciences, analytical chemistry, chemistry, biochemistry or other related disciplines. Superior laboratory skills in biological sample extraction, chromatography, and quantitative/qualitative Mass Spectrometry. Experience with bioanalysis of different molecular formats such as small molecules, peptides, oligonucleotides and/or proteins. Self-motivated with a proactive mindset. Excellent communication skills, both written and oral. Ability to thrive in a multi-disciplinary and fast-paced research environment with tight deadlines. Experience with LC-MS-based ADME and/or bioanalytical assays. Familiarity with Analyst, Xcalibur, MassLynx and other Mass Spectrometry data-acquisition software packages is preferred. Experience with GraphPad Prism, WinNonlin, Promass, or BioPharma Finder. Knowledge of guidance for industry bioanalytical method validation. The Research Scientist's responsibilities will be: Develop robust LC-MS analytical methods for bioanalysis of different molecular formats such as small molecules, oligonucleotides, peptides and proteins. Implement high-resolution mass spectrometry-based metabolite profiling and identification platforms. Occasionally perform LC-MS-based small molecule biomarker analysis. Review complex LC-MS-based data sets and articulate findings to project teams. Maintain and troubleshoot lab instruments such as biological sample extraction systems, HPLC, and LC-MS. Contribute to the team's knowledge through updating scientific literature and discussions. If you are having difficulty in applying or if you have any questions, please contact Mike Raletz at m.raletz@proclinical.com. Ƶ is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies. Ƶ Staffing is an equal opportunity employer. INDSCIC #J-18808-Ljbffr