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Research Scientist

3 months ago

Rockville, United States Axle Full time

(ID: 2024-5243)

**Axle** is seeking a **_Research Scientist _**to join our vibrant team at the National Institutes of Health (NIH) supporting the **National Center for Advancing Translational Sciences (NCATS) located in Rockville, MD.**

**Benefits We Offer**:

- 100% Medical, Dental & Vision Coverage for Employees
- Paid Time Off and Paid Holidays
- 401K match up to 5%
- Educational Benefits for Career Growth
- Employee Referral Bonus
- Flexible Spending Accounts:

- Healthcare (FSA)
- Parking Reimbursement Account (PRK)
- Dependent Care Assistant Program (DCAP)
- Transportation Reimbursement Account (TRN)

**Overall Position Summary and Objectives **This task order will independently provide support services to satisfy the overall operational objectives of NCATS ETB.

**Deliverables**:

- Work products and documents related to designing, synthesizing and optimizing chemical probes for potency and solubility; devise synthetic routes to target molecules; produce desired chemical libraries. - Ad-Hoc
- Work products and documents related to carrying out scale-up of the chemical probes develop and produce chemical probers with linkers for conjugation to fluorescent reporters and other reporter groups. - Ad-Hoc
- Work products and documents related to producing research reports; conduct and write literature reviews; search chemical databases for journal articles, patents and related technologies; publish and present relevant projects. - Ad-Hoc
- Work products and documents related to coordinating projects being developed by external collaborators, proposing SAR strategies and monitoring their progress. - Ad-Hoc
- Work products and documents related to collaboration with the technology transfer office and external patent offices to provide the necessary information for filing patents in selected programs. - Ad-Hoc

**Work Details**:

- Advance the science through proposing and investigating new target projects for initiation based on novelty and relevance to human health. **2**:

- Work with staff on assay design and method development using an array or experimentation. **3**:

- Write technical reports and prepare manuscripts. **4**:

- Prepare oral presentations and posters for internal and external groups/conferences. **5**:

- Supports the planning and execution of research experiments in the context of the laboratory's overall research program.
- Evaluate new techniques, instruments, and software for potential incorporation into current SOP.
- Supports laboratory staff on research projects and techniques.
- Work with staff on the interpretation of experiments performed by research scientists.
- Work with postdoc/biological scientists to perform statistical analysis for research projects.
- Maintains laboratory equipment and the training of others in their use.
- Train staff on the proper usage of laboratory instruments and equipment.
- Calibrate, maintain and troubleshoot instruments and equipment in the laboratory.
- Operate, troubleshoot and train others to use laboratory equipment and software.
- Provide advice and assistance to users in designing experiments, using instrumentation, data acquisition and analysis, and preparing figures for publication.
- Assists in maintaining adequate space and facilities for ongoing and projected research studies.
- Manage scientific equipment and resources (e.g. reagents, stocks of frozen sells, animal samples) including acquisition, documentation and storage.
- Evaluates, analyzes and interprets research data, communicates results and methods in reports, presentations, and manuscripts.
- Oversee project data quality; analyze and interpret project data.
- Conduct bioinformatics data analyses and statistical analyses; prepare data for abstracts and manuscripts.
- Maintain a detailed and up-to-date electronic laboratory notebook detailing all experiments.
- Coordinates with junior staff to modify research protocols.
- Work with staff to confirm assay results and evaluate new techniques and instruments; search literature; propose, design and test alternative assays for difficult screening targets; confirm assay results; develop secondary assays.
- Coordinate projects being developed in the laboratory, proposing SAR strategies and monitoring their progress.
- Coordinate with IT staff on all software issues specific to the chemistry group and on all computer problems.
- Participate in establishing criteria and standards for others to follow in the planning, review and evaluation of bioinformatics research projects.
- Suggest alternative or complementary approaches to experiments.
- Presents research at national scientific meetings and symposia.
- Co-author manuscripts on research projects; publish in peer-reviewed journals.
- Write papers and abstracts detailing research efforts and results for publication in peer-reviewed journals; prepare PowerPoint presentations as appropriate.
- Give posters and presentations detailing work at regional and national scientific meetings.