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Staff Research Associate
3 months ago
Our research examines how hormonal signals affect tissue development and function. We are particularly interested in genetic diseases that affect the skeletal system (bone, cartilage, and muscle). We use a combination of human cell models and mouse models to study how genetic changes in hormone signaling affects skeletal formation. Our vibrant translational research program also uses advanced models such as microfluidic “organs on a chip” to assist with disease modeling, as well as human induced pluripotent stem cells, single cell RNA sequencing, and small molecule screening.
- The individual hired will have a number of responsibilities related to these overall goals. These include deriving and maintaining human stem cell cultures, maintaining a small mouse colony, handling and genotyping mice, and assisting with experiments. Techniques used will include the analysis of mouse models, in vitro and in vivo skeletal tissue analysis, cell culture, protein analysis, cloning, PCR analysis, single cell sequencing, and standard molecular biology techniques. The individual will also work closely with other members of our team to assist with human tissue sample collection and processing. In addition, the individual will act as a lab manager, assist with establishing and maintaining the overall function of the laboratory (including stocking supplies, ordering, and arranging for maintenance of equipment). The individual will also assist with grant writing and paper writing.-
For roles covered by a bargaining unit agreement, there will be specific rules about where a new hire would be placed on the range.
**Department Description**
- Our mission remains simple: to provide world-class endocrinology care in the clinic and lead the endocrine field in research. For over 50 years, the Division of Endocrinology and Metabolism at UCSF has been an international leader in both clinical endocrinology and basic endocrine research. We bring the questions and unknowns from our patient's bedside to the research laboratory, not only to improve our understanding of the disease process, but to develop new therapeutic modalities. We then bring the advances of the laboratory back to our patients.
- Endocrinology at UCSF Medical Center was ranked fourth in the nation, according to U.S. News & World Report. Our Endocrinology Clinic and metabolism services include comprehensive consultation and treatment for patients with known or suspected hormonal disorders. ABOUT UCSF The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences, health professions and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences.
**Required Qualifications**
- SRA 1:
- BA/BS in biomedical research or related science and knowledge of, or experience with, the basic techniques or methods required by the position; and/or an equivalent combination of education and experience;
- Recent (within the past two years) direct laboratory experience using the techniques or methods required by the position.
- Knowledge of laboratory, biohazard and radiation safety is required since the individual will be working in a BSL2* environment with hazardous agents, infectious agents, and radiological materials.
- Knowledge of and experience with PCR and basic molecular biology techniques, including cloning, bacterial cultures/propagation, plasmid isolation
- Formal undergraduate coursework in molecular biology or experience in a molecular biology research laboratory
- Computer skills including the use of Microsoft office programs (Excel and Word), Adobe Photoshop, and sequence analysis programs (Vector NTI or equivalent)
- Careful attention to detail. Maintain a detailed laboratory notebook of experiments done on a daily basis
- Ability to work independently and to assess need for interaction with supervising faculty member
- Strong quantitative skills
- Strong organizational ability and aptitude to follow laboratory standard operating procedures; ability to process and maintain databases to help organize the laboratory.
- Strong oral and written communication skills, including data presentation, the preparation of tables, charts, and graphs, and the fundamentals of statistical analysis
- Demonstrated ability to work as part of a scientific research team
- Managerial skills (basic accounting and stocking experience)
- Ability to work independently and to assess need for interaction with supervising faculty member; knowledge of and experience with lab management, training lab personnel
- Quick learner, shows initiative, works very well with others in a collaborative setting, works very efficiently, can prioritize and multitask
- Basic knowledge of data presentation, including the preparation of tables, charts, graphs and the fundamentals of statistical analysis
SRA 2:
- In add
