Scientist I/ii

2 weeks ago


Cambridge, United States Nvelop Therapeutics Full time

**Position Overview**

**Responsibilities**:

- Significantly contribute to in vivo study methodologies including dose preparation of test articles, IV/RO injections, retro-orbital blood sampling, necropsy at EOS.
- Work closely with the _in vivo_ pharmacologist aspects of multiple projects within discovery and development.
- Propose, plan, coordinate, and supervise study execution at external Contract Research Organizations (CROs).
- Develop and implement new animal models to improve _in vivo_ pharmacology studies.
- Write Institutional Animal Care and Use Committee (IACUC) protocols and ensure compliance.
- Analyze data from _in vivo_ pharmacology and efficacy studies.
- Contribute to study reports, potential regulatory filings, and project presentations.
- Maintain excellent written documentation of completed experiments.

**Who you are**:

- Ph.D. in Biology, Immunology, Pharmacology, or related fields with 0 - 5 years post graduate experience, or BSc with 5 plus year experience in industry
- Extensive hands-on experience and familiarity with _in vivo_ animal models, including manipulation, dosing, necropsy, and tissue dissociation.
- Have experience working with tissue dissociation and _ex vivo_ samples.
- Have experience with multicolor flow cytometry.
- mammalian cell culture, in vitro assay designs, and related cell/molecular biology methods is a plus.
- Experience with multicolor and high dimensional flow cytometry is a plus.
- Strong problem-solving, organization, and communication skills
- Ability to work independently as well as part of a team.
- Ability to adapt to a fast-paced environment and pivot to support ongoing needs.



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