Principal Scientist I

6 days ago


Cambridge, United States Novartis Full time

**Summary**:
**About the Role**:
**Key Responsibilities**:

- Develop in vivo CDX, PDX, and syngeneic models to evaluate anti-tumor activity, PK/PD relationships, relevant biomarkers, and key translational questions.
- Manage associate-level scientists.
- Collaborate with cross-functional project teams.
- Critically analyze and present results within a multidisciplinary team environment
- Careful adherence to animal protocols and proper documentation of data and methods in electronic laboratory notebook

Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between $112,800 - $169,200/year for the Principal Scientist I and $124,000 - 186,000 for the Principal Scientist II. While salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Novartis EVP Manifesto.mp4

**Essential Requirements**:

- This position will be located at the Cambridge, MA site and will not have the ability to be located remotely. This position will not require travel.
- For Principal Scientist II position: PhD with 5-8 years of research experience as a postdoc or in the pharmaceutical/biotech industry
- For Principal Scientist I position: PhD with 3-5 years of research experience as a postdoc or in the pharmaceutical/biotech industry
- Extensive experience in a variety of molecular biology and flow cytometric skills.
- Strong knowledge of T-cell and/or myeloid biology
- Extensive experience working with CDX and PDX xenograft tumor models and/or syngeneic models
- Expertise in cell culture, PCR, ELISA, western blot, and flow cytometry
- Strong analytical, communication (written and verbal), and organizational skills, including a proficiency with PowerPoint and commonly used data analysis programs, such as Excel and Prism
- A highly motivated, inquisitive, and creative individual, who thrives in a highly-matrixed work environment, and can effectively communicate within multidisciplinary project teams.

**Desirable Requirements**:

- A strong background and expertise in cancer immunology is preferred.

**Commitment to Diversity and Inclusion**:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Division

Biomedical Research

Business Unit

Pharma Research

Location

USA

Site

Cambridge (USA)

Company / Legal Entity

U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.

Functional Area

Research & Development

Job Type

Full time

Employment Type

Regular

Shift Work

No



  • Cambridge, United States Novartis Full time

    **Summary**: Internal Job Title: Principal Scientist I Role Location: Cambridge, MA, onsite About the role: We are seeking a motivated scientist with expertise in nephrology to join a vibrant research team focused on finding new transformative therapies for people living with renal disease. In this role, you will be responsible for driving research...

  • Principal Scientist

    2 weeks ago


    Cambridge, Massachusetts, United States Newton Colmore Consulting Full time

    Principal Scientist - Protein Engineering - Cambridge, MA Newton Colmore is partnered with a biotech company in Cambridge MA, and we are searching for a principal-level scientist with expertise in protein engineering. As a Principal Scientist within this organisation, you will be utilising your expertise to design and execute protein engineering strategies,...


  • Cambridge, United States Johnson & Johnson Full time

    Johnson and Johnson is recruiting for a **Principal Scientist, Immunopeptidomics & Proteomics **for our site located in Cambridge, MA. **Primary responsibilities**: - Manage a team of wet lab scientists enabling proteomic insights across a wide variety of programs and therapeutic modalities. - Plan, oversee and perform wet lab proteomic activities for...


  • Cambridge, United States Repertoire Immune Medicines Full time

    Job DescriptionJob DescriptionPrincipal Scientist, Protein Production and Process DevelopmentCompany OverviewRepertoire Immune Medicines is a biotechnology company working to unlock and direct the remarkable power of the human immune system to treat cancer, autoimmune disease and infectious disease. The company was founded by Flagship Pioneering on the...


  • Cambridge, United States Repertoire Immune Medicines Full time

    Job DescriptionJob DescriptionPrincipal Scientist, Protein Production and Process DevelopmentCompany OverviewRepertoire Immune Medicines is a biotechnology company working to unlock and direct the remarkable power of the human immune system to treat cancer, autoimmune disease and infectious disease. The company was founded by Flagship Pioneering on the...


  • Cambridge, United States Proclinical Full time

    Principal Associate Scientist for Analytical Development - Contract - Cambridge, MA Proclinical is actively seeking a Principal Associate Scientist. This is a temporary contract position based in Cambridge, Massachusetts, MA. Primary Responsibilities:This role is primarily focused on the initial characterization testing, annual re-qualification, and trending...


  • Cambridge, United States Proclinical Staffing Full time

    Principal Associate Scientist for Analytical Development - Contract - Cambridge, MA Proclinical is actively seeking a Principal Associate Scientist. This is a temporary contract position based in Cambridge, Massachusetts, MA. Primary Responsibilities:This role is primarily focused on the initial characterization testing, annual re-qualification, and trending...


  • Cambridge, United States AbbVie, Inc Full time

    Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services...


  • Cambridge, United States AbbVie, Inc Full time

    Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services...


  • Cambridge, United States Raytheon Technologies Corporation Full time

    Date Posted:2024-04-03 Country:United States of America. Location:MA 105: BBN Headquarters 10 Moulton Street , Cambridge, MA, 02138 USA - Position Role Type:Onsite. At Raytheon, the foundation of everything we do is rooted in our values and a highe Research Scientist, Research, Business Development, Principal, Scientist, Cybersecurity, Manufacturing,...


  • Cambridge, United States Raytheon Technologies Corporation Full time

    Date Posted:2024-04-03 Country:United States of America. Location:MA 105: BBN Headquarters 10 Moulton Street , Cambridge, MA, 02138 USA - Position Role Type:Onsite. At Raytheon, the foundation of everything we do is rooted in our values and a highe Research Scientist, Research, Business Development, Principal, Scientist, Cybersecurity, Manufacturing,...


  • Cambridge, United States DeepRec.ai Full time

    Principal Machine Learning Scientist (Large Language Models)Location: Hybrid in Cambridge, Massachusetts, USADeepRec.ai seeks a dedicated Principal level Machine Learning Scientist specializing in Large Language Models (LLMs), to join our client's innovative team in Cambridge, Massachusetts.You will be part of an agile, cross-functional team responsible for...


  • Cambridge, Massachusetts, United States Beam Therapeutics Full time

    Position Overview Beam is seeking a principal scientist with expertise in nanoparticle process and formulation development team. An ideal candidate would have good understanding of late-stage drug product process development. In this role, the individual will work closely with the Discovery, Technical Development, Manufacturing and Analytical groups to...


  • Cambridge, Massachusetts, United States Beam Therapeutics Full time

    Position Overview Beam is seeking a principal scientist with expertise in nanoparticle process and formulation development team. An ideal candidate would have good understanding of late-stage drug product process development. In this role, the individual will work closely with the Discovery, Technical Development, Manufacturing and Analytical groups to...


  • Cambridge, Massachusetts, United States Beam Therapeutics Full time

    Position Overview Beam is seeking a principal scientist with expertise in nanoparticle process and formulation development team. An ideal candidate would have good understanding of late-stage drug product process development. In this role, the individual will work closely with the Discovery, Technical Development, Manufacturing and Analytical groups to...


  • Cambridge, Massachusetts, United States Cerevel Therapeutics Full time

    Company OverviewCerevel Therapeutics is dedicated to unraveling the mysteries of the brain to treat neuroscience diseases. We are tackling neuroscience diseases with a differentiated approach that combines expertise in neurocircuitry with a focus on receptor selectivity. Our portfolio of pre-commercial neuroscience assets targets a broad range of central...


  • Cambridge, United States Cerevel Therapeutics Full time

    Company Overview Cerevel Therapeutics is dedicated to unraveling the mysteries of the brain to treat neuroscience diseases. We are tackling neuroscience diseases with a differentiated approach that combines expertise in neurocircuitry with a focus on receptor selectivity. Our portfolio of pre-commercial neuroscience assets targets a broad range of central...


  • Cambridge, Massachusetts, United States Cerevel Therapeutics Full time

    Company OverviewCerevel Therapeutics is dedicated to unraveling the mysteries of the brain to treat neuroscience diseases. We are tackling neuroscience diseases with a differentiated approach that combines expertise in neurocircuitry with a focus on receptor selectivity. Our portfolio of pre-commercial neuroscience assets targets a broad range of central...


  • Cambridge, United States AbbVie Full time

    Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services...


  • Cambridge, United States AbbVie Full time

    Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services...