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Scientist I
4 months ago
Make your mark for patients
UCB's Gene Therapy Vector Core team is seeking a Scientist I - Bioreactor & NGS to join a group focused on AAV upstream process development. The candidate will work across functional teams and will be responsible for bioreactor operations for research grade AAV production to support gene therapy platform development activities; including capsid engineering platform. This is an onsite position and will be based out of our Bedford, MA location,
NOTE: We are interested in every qualified candidate who is eligible to work in the United States. However, we are not able to sponsor visas at any point for this role. This includes taking over sponsorship for an existing Visa.
Major Responsibilities:
- Production of AAV vectors using batch or perfumion mode in bioreactors up to 50L
- Characterization of packaged AAV genome by next generation sequencing (NGS)
- Support gene therapy platform development activities by applying upstream expertise
- Good practices of data record keeping
- Collaborate with the vector biology and downstream process development teams
- Ability to function independently and cross functionally across various UCB teams (data scientists, cell biologists, , disease area experts, etc)
Minimum Requirements:
BS degree in Biology, Biomanufacturing or related field with 8 years of experience - OR - MS degree with 6 years of experience - OR - PhD or Post Doc with relevant academic research experience Hands-on AAV experience in industry and/or academia Demonstrated past experience of either one of the following skills:- Upstream unit operation mastery at various scales with biologics or for viral gene therapy applications.
- Next generation sequencing experience for characterization of libraries
Additional Preferred Experience/Skills:
MS with Biochemical Engineering or Biomanufacturing degree with direct AAV production experience in bioreactors3+ years of experience with process development of AAV vectors3+ years of hands on experience with NGS library preparation, PacBio data acquisition, analysis and QCAt least 1 year experience in drug discovery in a pre-clinical settingCompensation Range:
$96,480 to $126,630
Internal applicants should be in their current job for at least 12 months, must meet performance standards and are not on formal corrective/disciplinary process (PIP), warning, final warning, or compliance warning letters within the last 12 months. Please inform your Manager or your Talent Partner before applying to any internal job opportunities.
As an Equal Opportunity Employer, we are open to all talent, and adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on US- for application to US based roles. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.
Requisition ID: 87419
Recruiter: John Gasbarre
Hiring Manager: Douglas Blanton
Talent Partner: Sandra Jeanne Rogers
Job Level: SA II
Please consult HRAnswers for more information on job levels.
