Principal Scientist, Translational Modeling
2 weeks ago
**About the Role**:
The position is located in Cambridge, MA and will not have the ability to be located remotely.
LI-Hybrid
About the role:
We are seeking an experienced translational modeler eager to accelerate drug discovery & development by facilitating rigorous decision making with modeling & simulation, from target identification to first-in-human studies and beyond. You will work in a multi-disciplinary environment with opportunities to engage in projects that span different therapeutic modalities.
This role reports to a PK Sciences Translational Modeling team lead within Translational Medicine in Biomedical Research.
Key responsibilities:
- Act as the Translational M&S representative on programs in oncology, developing and executing modeling strategies, contributing to project team discussions, and guiding therapeutic design and dose selection decisions.
- Advance the development of integrated modeling platforms that bridge data and knowledge across preclinical species and patients, partnering with discovery project teams as well as the preclinical safety and pharmacometrics groups.
- Proactively seek opportunities to increase the impact and awareness of translational modeling through communications with internal and external audiences.
**Diversity & Inclusion / EEO**:
- We are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential._
**Role Requirements**:
Essential requirements:
Prior experience in quantitative systems pharmacology (QSP), pharmacokinetics and pharmacodynamics (PKPD), and/or physiologically based PK (PBPK) modeling is strongly preferred.
Expert level proficiency in core modeling fundamentals is required, including scripting languages (e.g., MATLAB, R), construction of ordinary differential equation (ODE) models, parameter estimation, and data visualization.
Demonstrated ability to communicate modeling results to a multidisciplinary audience to facilitate strategy and decision-making.
Fluent in English (oral and written).
ModelingAndSimulation #PKSciences #TranslationalMedicineQuants
You’ll receive:
You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook.
Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve.
Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between $130,400 - $195,600/year; however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Division
Biomedical Research
Business Unit
Translational Medicine
Location
USA
Site
Cambridge, MA
Company / Legal Entity
NIBRI
Functional Area
Research & Development
Job Type
Full Time
Employment Type
Regular
Shift Work
No
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